Senior Full Stack Software Engineer San Francisco (Brisbane), CA

Vivodyne, Inc.; San Francisco (CA); Hybrid; USD 204,000 - 286,000; Full time

Job summary

Vivodyne, Inc. is seeking a Senior Full-Stack Software Engineer to build high-performance React apps with a FastAPI backend and a Postgres database. You will lead frontend architecture, own features end-to-end, and collaborate with product, scientists, and AI researchers to ship quickly in a biotech platform.

You’ll work onsite in Brisbane, CA, near precision robotics and lab equipment, applying data-dense interfaces to empower drug discovery and human health.

Qualifications

• 5+ years building complex React applications with sophisticated state management.
• Fluency in TypeScript.
• Experience developing applications that render and annotate imagery is highly valued.
• Working knowledge of Python and Postgres in production.
• Excellent communication skills and cross-disciplinary collaboration.

Responsibilities

• Frontend-Led Full-Stack Development: architect and build complex React/TypeScript interfaces and backend integration points in Postgres.
• User Experience: create clean, responsive interfaces translating complex requirements into intuitive designs.
• Code Quality & Best Practices: write well-tested, maintainable code with focus on scalability and performance.
• Collaboration & Communication: work with scientists, engineers, and AI researchers to gather requirements and deliver solutions.
• High Velocity / AI Accelerated Development: leverage LLMs and agentic tools to ship reliable code quickly; balance prototyping with robust implementations.

Skills

React

TypeScript

Postgres

API design

Data modeling

Frontend architecture

Python

TanStack

Education

Bachelor’s or Master’s in Computer Science (or related field)

Tools

FastAPI

PostgreSQL

Pydantic

Job description

Vivodyne creates human data before clinical trials.

We accelerate the successful discovery, design, and development of human therapeutics by testing on large, lab-grown human organ tissues at massive scale, driving technological advancement at the convergence of novel biology, robotics, and AI. We identify and validate new therapeutic targets and de-risk new therapeutic assets by producing clinically translatable multi-omic data from our proprietary, physiologically-realistic human organ tissues at unprecedented scale, speed, and quality. This enables us to produce more human data than all clinical trials in the U.S. combined. We’re financially backed by some of the most selective and successful venture funds, and we have already partnered with a majority of the top 10 multinational pharmaceutical companies to discover and develop better, safer drugs and dramatically reduce the burden of animal testing.

We’re looking for an exceptional Senior Full-Stack Software Engineer to work hand in hand with our Product team to build polished, high-performance web applications using React with FastAPI on the backend and Postgres as a database.

The ideal candidate leads with deep frontend expertise in building sophisticated, stateful UIs in React/TypeScript, while bringing enough backend fluency to own features end-to-end. You'll build rich, data-dense interfaces for scientific workflows where getting the interaction design and state management right is the hard part. Additionally, the ideal candidate is an 'AI native' and uses their strong technical expertise to augment the prototyping speed provided by LLMs. You'll ship deliverables in days, not months, and have a sharp instinct for system architectures that achieve rapid delivery and robust performance.

You will be a core contributor to shaping our next-generation biotech platform that discovers and tests new drugs on lab-grown human tissues.

Own the building of scientific experiment design and results-monitoring tools that, together with our platform, have enabled Vivodyne to partner with a majority of the top-10 pharmaceutical companies in making better, safer cures to complex human diseases. You will be expected to deliver web applications that align with well-designed frames/user flows and product requirements that help scientists interact seamlessly with our unique datasets, robotic systems, and lab-grown tissues.

You’ll have the opportunity to work at the cutting edge of biotech and software engineering, collaborating with teams spanning tissue engineering, robotics, and AI. You'll be working a few feet away from large precision robots, laser microscopes, and robot arms, surrounded by an exceptionally talent-dense team of experts from multiple scientific disciplines.

You will be able to focus on building internal products and tools with incredible functionality, surrounded by sophisticated end users directly appreciative of the products you build---without needing to do integration testing for first-gen Chromebooks or handle bug reports from Fire tablets.

While bringing a passion and exquisite skill for building and shipping high-quality applications that drive scientific discovery, you'll be involved firsthand in the advancement of human health, you'll watch thousands of human organ tissues grow before your eyes, and join an intense, fun, fast-moving team in shaping the future of human health.

Responsibilities

Frontend-Led Full-Stack Development — Architect and build complex React/TypeScript interfaces for scientific workflow applications; own backend integration points via API design and data layer work in Postgres.

User Experience — Create clean, responsive, and user-focused interfaces that translate complex requirements into intuitive designs, establishing best practices for component architecture and state management patterns.

Code Quality & Best Practices — Write well-tested, maintainable code with a focus on scalability, performance, and cost-efficiency.

Collaboration & Communication — Work closely with scientists, engineers, and AI researchers to gather requirements, provide updates, and deliver impactful solutions.

High Velocity / AI Accelerated Development — Leverage leading language models and agentic tools like Claude Code and Codex, or similar to ship reliable code quickly; maximize prototyping and component design velocity while balancing robustness of implementations

Requirements and Expectations

Technical Excellence

• Deep expertise in React, TypeScript, and modern frontend architecture (component composition, state management, performance profiling).
• Proficient in building visually appealing, high-performance React applications.
• Strong CSS/styling architectural skills (CSS modules, Tailwind etc.)
• Strong data modeling skills for biotech applications, translating scientific needs into structured schemas.
• Comfortable in API design, schema definition, and query optimization with Postgres.
• Solid foundation in data structures, algorithms, and software architecture (CS degree preferred).

Accountability & Problem-Solving

• Own full-stack development, ensuring high-quality, tested, and timely feature delivery.
• Balance speed and rigor to solve complex engineering challenges, from large-scale data ingestion to optimizing imagery metadata.
• Work cross-functionally with scientists, engineers, and AI researchers, aligning technical solutions with user needs.

Delivering Results

• Manage time effectively, handling multiple priorities while shipping production-ready features.
• Champion best practices, maintain clear documentation, and uphold high coding standards.
• Design scalable, reliable systems while anticipating and addressing bottlenecks.
• Leverage open-source and existing frameworks to optimize development.

Leadership & Influence

• Mentor junior engineers through code reviews and knowledge sharing.
• Advocate for full-stack best practices to drive scientific and business impact.

Qualifications

• Bachelor’s or Master’s in Computer Science (or related field), or equivalent experience.
• 5+ years building complex React applications with sophisticated state management, not just simple CRUD interfaces.
• Fluency in TypeScript. Knowledge of TanStack ecosystem is a bonus.
• Experience Developing Applications that Render and Annotate Imagery is highly valued.
• Comfortable working with APIs and understanding the data layer.
• Working knowledge of Python (e.g. Pydantic, FastAPI).
• Working knowledge of Postgres in production environments.
• Experience in High-throughput Laboratory Automation or Robotics is highly valued.
• Excellent Communication Skills for conveying technical concepts and aligning stakeholder expectations.
• Project Delivery Experience in fast-paced environments; comfortable balancing shifting priorities and multiple projects.
• Proven Ability to collaborate across disciplines, from biology to automation to AI, delivering high-impact results.
• Track Record of shipping secure, maintainable, and well-tested code.

Vivodyne, Inc. is an equal opportunity employer. Vivodyne complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.

Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location.

Pay Range

$204,400 - $285,600 USD

This is an on-site based role; our office is located in Brisbane, California

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Vivodyne’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.