Senior Engineer, Small Molecule Process Development and Manufacturing

Biogen; Cambridge (MA); On-site; USD 138,000 - 185,000; Full time

Benefits offered by this job

Medical Insurance

Dental Insurance

Vision Insurance

401(k) with match

Tuition reimbursement

Employee Stock Purchase Plan

Paid vacation & holidays

Job summary

Biogen in Cambridge seeks a Senior Engineer to join the Small Molecule Chemical Development team. You will help design and scale robust processes for diverse drug modalities, collaborating with chemists and engineers to deliver candidates for clinical trials.

Responsibilities include experimental design, data sharing, and technology transfer from lab to manufacturing partners, with opportunities for leadership and mentoring within a results-driven, inclusive culture.

Qualifications

• Ph.D. with 5+ years of relevant experience in pharma/biotech settings.
• M.S. with 6+ years of relevant experience in pharma/biotech settings.
• B.S. with 7+ years of relevant experience in pharma/biotech settings.
• Strong background in pharmaceutical chemical engineering, crystallization, process safety, and tech transfer.

Responsibilities

• Design and conduct lab experiments to optimize and characterize processes.
• Develop and execute experiments to advance the portfolio and analyze data for robust processes.
• Manage key laboratory instrumentation.
• Develop knowledge for transitioning lab-scale processes to manufacturing partners.
• Collaborate with Process Chemistry, Analytical Chemistry, Solid Form, and Separations teams to support clinical material supply and regulatory filings.
• Write research reports, present data in team meetings, and contribute to CMC activities including IND sections.
• Interact with Contract Research Organizations as needed.
• Initiate innovative research projects to improve process understanding and control.
• Mentor and guide earlier career team members.

Skills

Crystallization

Process characterization

Process safety

Tech transfer

Analytical tools

Purification techniques

Independent work

Communication

Education

Ph.D.

M.S.

B.S.

Job description

About This Role:

We are seeking a highly motivated and creative Chemical Engineer to join our Small Molecule Chemical Development team. This position provides an exciting opportunity to develop robust processes for the synthesis of a wide range of assets across various modalities. As a Senior Engineer, you will gain experience in early to late-phase drug development and exposure to designing and developing manufacturing processes for clinical and commercial therapeutics. You will collaborate with a team of organic chemists and chemical engineers in designing innovative processes that supply new medicines to patients.

Who We Are:

We are a team of organic chemists and chemical engineers engaged in the design of innovative processes which supply new medicines to patients. We focus on developing safe, economical, sustainable, cost-effective, and robust processes to support clinical trials and the launch of new medicines across various drug modalities. We are driven by first principles science, data-driven decision-making, and collaborative teamwork.

What You’ll Do:

• Collaborate with development and manufacturing teams to design and conduct laboratory experiments aimed at optimizing and characterizing processes.
• Design and execute experiments to advance the portfolio, analyzing and sharing data to implement efficient and robust chemical processes.
• Manage key laboratory instrumentation
• Develop fundamental process knowledge for transitioning processes from lab scale to manufacturing partners.
• Collaborate with Process Chemistry, Analytical Chemistry, Solid Form, and Separations colleagues to support clinical material supply and regulatory filings.
• Write research reports, present data in team meetings, and engage in CMC activities, including authoring CMC sections of INDs.
• Interact with Contract Research Organizations as project needs evolve.
• Initiate innovative research projects to improve process understanding and control.
• Mentor and guide earlier career team members.

Who You Are:

You have a passion for exploring novel scientific concepts and are eager to contribute to the design, development, and execution of cutting-edge technologies in the service of delivering drug candidates for clinical trials. Your vision and dedication drive you to push the boundaries of scientific endeavors, ultimately impacting patient lives. You thrive in a collaborative environment where urgency, accountability, inclusion, and integrity are shared values.

Required Skills:

• Ph.D. with 5+ years of relevant experience.
• M.S. with 6+ years of relevant experience in pharmaceutical or biotech settings.
• BS with 7+ years of relevant experience in pharmaceutical or biotech settings.
• Strong background in pharmaceutical chemical engineering, including crystallization techniques, process characterization, process safety, and tech transfer protocols.
• Experience in crystallization of APIs and familiarity with analytical tools and purification techniques.
• Ability to work both independently and collaboratively.
• Good communication skills and the desire to work in a collaborative team environment.

Preferred Skills:

• Experience with process characterization, crystallization techniques, drug substance form control, and familiarity with process safety protocols.
• Demonstrated problem-solving skills in pharmaceutical chemical engineering.

Additional Information

The base compensation range for this role is: $138,000.00-$185,000.00

Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.

Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognise your future potential based on individual, business unit and company performance.

In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being; including, but not limited to:

• Medical, Dental, Vision, & Life insurances
• Fitness & Wellness programs including a fitness reimbursement
• Short- and Long-Term Disability insurance
• A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
• Up to 12 company paid holidays + 3 paid days off for Personal Significance
• 80 hours of sick time per calendar year
• Paid Maternity and Parental Leave benefit
• 401(k) program participation with company matched contributions
• Employee stock purchase plan
• Tuition reimbursement of up to $10,000 per calendar year
• Employee Resource Groups participation

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about Biogen.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.

Job Level: Management