Senior Engineer I, Manufacturing Sciences - Purification

Biogen; Milwaukee (WI); On-site; USD 98,000 - 127,000; Full time

Benefits offered by this job

Medical, Dental, Vision, & Life ins.

Fitness & Wellness programs

Paid vacation and year-end shutdown

Up to 12 holidays + 3 days Personal

Tuition reimbursement up to $10,000

Employee stock purchase plan

Job summary

Biogen is seeking a Senior Engineer I, Manufacturing Sciences to serve as a scientific resource for biologics purification at our RTP facility. You will design and execute studies, lead downstream transfers into GMP manufacturing, and support ongoing commercial operations.

You will collaborate with cross-functional teams across Technical Development, Engineering, and GMP Manufacturing to drive process understanding and continuous improvement.

Qualifications

• Bachelor’s degree in a scientific or technical field from an accredited institution.
• At least 4 years of directly relevant industry experience.
• Familiarity with biopharmaceutical manufacturing or downstream processing.
• Experience designing experiments, analyzing data, and executing laboratory studies.
• Willingness to work on-site during training, critical projects and audits.

Responsibilities

• Provide deep technical expertise in biologics purification to support tech transfer and improvements.
• Plan, execute, and document lab studies to improve process robustness and troubleshooting.
• Lead cross-functional teams with Technical Development, Engineering, and GMP Manufacturing.
• Support downstream GMP operations including process transfer activities and campaigns.
• Act as SME for investigations, performing root cause analysis and CAPAs.
• Represent manufacturing in change controls, continuous improvement, and capital projects.
• Support process validation activities including batch execution and technical reports.
• Analyze data and communicate insights to stakeholders.

Skills

Biopharm manufacturing familiarity

Downstream processing

Design experiments

Data analysis

On-site readiness

Project leadership

Root cause analysis

CAPA

Regulatory documentation

SME in manufacturing

Education

Bachelor’s degree in a scientific or technical field

Bachelor’s degree in engineering or life science (preferred)

Job description

About This Role

The Senior Engineer I, Manufacturing Sciences serves as a key scientific resource supporting biologics purification for drug substance manufacturing at Biogen’s RTP facility. This role enables successful production of biopharmaceuticals by designing and executing laboratory studies, leading downstream process transfers into GMP manufacturing, and providing scientific support to ongoing commercial operations.

The Senior Engineer I, Manufacturing Sciences serves as a key scientific resource supporting biologics purification for drug substance manufacturing at Biogen’s RTP facility. This role enables successful production of biopharmaceuticals by designing and executing laboratory studies, leading downstream process transfers into GMP manufacturing, and providing scientific support to ongoing commercial operations.

What You’ll Do

• Provide deep technical expertise in biologics purification: chromatographic separations, viral filtration, and UF/DF to support technology transfer and process improvement initiatives
• Design, plan, execute, and document laboratory studies to improve process robustness, enhance process understanding, and troubleshoot manufacturing issues
• Lead cross-functional project teams and collaborate with Technical Development, Engineering, and GMP Manufacturing
• Support downstream GMP operations, including process transfer activities and ongoing manufacturing campaigns
• Serve as technical SME for investigations, performing root cause analysis and implementing effective corrective and preventive actions (CAPAs)
• Represent manufacturing in change controls, continuous improvement initiatives, capital projects, and new component introductions
• Support process validation activities, including batch execution and authoring technical summary reports
• Analyze manufacturing data and experimental results, clearly communicating insights and recommendations to stakeholders

Who You Are

You are a hands-on, scientifically driven problem solver with experience in mammalian cell culture. You thrive in collaborative environments, enjoy working with complex data, and are motivated to improve manufacturing processes through practical, data-driven solutions.

Required Skills

• Bachelor’s degree in relevant scientific or technical fields from an accredited college or university
• At minimum 4 years of directly relevant industry or industry-adjacent experience
• Familiarity with biopharmaceutical manufacturing and/or downstream processing
• Previous experience with some or all of the following: design experiments, analyze data, and/or execute laboratory studies
• Willingness and ability to work on-site more frequently during training periods, critical projects, audits, etc.

Preferred Skills

• Bachelor’s degree in engineering or life science
• Demonstrated experience leading complex scientific projects related to purification
• Previous experience performing root cause analysis and risk-based technical assessments
• Experience supporting deviations, change controls, CAPAs, and regulatory documentation
• Prior experience acting as a technical lead or SME within a manufacturing support organization

Job Level: Professional

Additional Information

The base compensation range for this role is: $98,000.00-$127,000.00

Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.

Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.

Benefits

In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being; including, but not limited to:

• Medical, Dental, Vision, & Life insurances
• Fitness & Wellness programs including a fitness reimbursement
• Short- and Long-Term Disability insurance
• A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
• Up to 12 company paid holidays + 3 paid days off for Personal Significance
• 80 hours of sick time per calendar year
• Paid Maternity and Parental Leave benefit
• 401(k) program participation with company matched contributions
• Employee stock purchase plan
• Tuition reimbursement of up to $10,000 per calendar year
• Employee Resource Groups participation

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our Biogen.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.