Senior Drug Product Engineer, Process Development

BioSpace; Brisbane (CA); On-site; USD 195,000 - 223,000; Full time

Job summary

Nurix Therapeutics seeks a Principal Engineer to own hands-on process development for small-molecule drug product manufacturing, leading scale-up and CDMO operations for late-stage and commercial programs. You will drive technology transfer, QBD/DOE studies, and regulatory batch activities with QA, Chemical Development, and Global Supply Chain partners.

Applicants should have a Ph.D. in chemical engineering (or equivalent) with 8+ years of industry experience in GMP DP development, CDMO

Qualifications

• Ph.D. in chemical engineering or related field with at least 8 years of industrial, late-phase, small-molecule drug product development experience.
• Extensive GMP oral solid dose form manufacturing knowledge (spray drying, tableting, encapsulation).
• Extensive third-party drug product CDMO management experience, including tech transfer, QBD and DOE studies, clinical supply, registration batches, and commercial launches.

Responsibilities

• Provide engineering leadership for small-molecule drug product process development and optimization for CDMOs and scale-up.
• Lead equipment engineering and operations at drug product CDMOs, including technology transfer and process validation.
• Coordinate with CDMOs and Nurix QA, Chemical Development, and Global Supply Chain for timely DP manufacture and release.

Skills

Process development leadership

Scale-up

CDMO management

QBD

DOE studies

Regulatory knowledge

GMP experience

Technical mentorship

Cross-functional collaboration

Education

Ph.D. in chemical engineering

M.S. in chemical engineering

B.S. in chemical engineering

Job description

Nurix Therapeutics seeks a Principal Engineer to own hands-on process development for small-molecule drug product manufacturing, leading scale-up and CDMO operations for late-stage and commercial programs. You will drive technology transfer, QBD/DOE studies, and regulatory batch activities with QA, Chemical Development, and Global Supply Chain partners.

Applicants should have a Ph.D. in chemical engineering (or equivalent) with 8+ years of industry experience in GMP DP development, CDMO