Senior Drug Product Development Scientist - Oral Solids

Sanofi; Cambridge (MA); On-site; USD 110,000 - 140,000; Full time

Benefits offered by this job

Health benefits

Wellbeing programs

Parental leave

Job summary

Sanofi in Cambridge, MA is seeking a Senior Associate Scientist in Drug Product Development to advance oral solid dosage formulations from preclinical to GMP manufacturing readiness, collaborating across CMC teams and external partners.

You will design experiments, execute DoE, and contribute to scale-up; perform dissolution and solubility studies, develop enabling formulations, and maintain rigorous documentation and safety practices in a fast-paced, cross-functional environment.

Qualifications

• 4+ years (Bachelor) or 2+ years (Master) hands-on pharmaceutical product/process development experience.
• Experience with oral solid dosage formulation (tablets/capsules).
• Experience running dissolution studies (USP2/USP4/USP7) and/or Pion equipment.
• Solubility testing experience.
• Industry experience preferred; academic work is acceptable with industry relevance.

Responsibilities

• Support the design and development of oral solid dosage formulations (tablets, capsules, granules) for preclinical and clinical programs
• Execute formulation studies including excipient compatibility testing, prototype development, and formulation optimization under guidance
• Contribute to conventional and enabling formulations (e.g., amorphous dispersions) to address bioavailability challenges
• Support formulation and process development activities, including granulation, blending, compression/tableting, and encapsulation
• Assist in applying DoE methodologies to optimize formulation and process parameters
• Collaborate within the CMC team and support defined deliverables and milestones
• Work with Analytical, Biopharm, Quality, and Regulatory colleagues to align development strategies
• Support Research interactions to evaluate molecular attributes relevant to drug delivery and formulation design
• Author and review technical reports, batch records, and supporting documentation
• Ensure documentation is accurate, complete, and compliant
• Maintain awareness of current scientific literature
• Plan standard and moderately complex experiments with limited guidance

Skills

Oral solid dosage

Dissolution studies

Solubility testing

DoE methodologies

Scale-up

Technology transfer

Cross-functional teamwork

Analytical mindset

Communication skills

Education

Bachelor's in Pharmaceutical Sciences

Master's in related field

Tools

Tablet presses

Granulation equipment

Capsule filling

Coating equipment

Dissolution apparatus

Job description

Sanofi in Cambridge, MA is seeking a Senior Associate Scientist in Drug Product Development to advance oral solid dosage formulations from preclinical to GMP manufacturing readiness, collaborating across CMC teams and external partners.

You will design experiments, execute DoE, and contribute to scale-up; perform dissolution and solubility studies, develop enabling formulations, and maintain rigorous documentation and safety practices in a fast-paced, cross-functional environment.