Senior Distinguished Scientist for Transgenic Model and Technology

Eacademy Sanofi; Cambridge (MA); On-site; USD 120,000 - 160,000; Full time

Benefits offered by this job

Competitive compensation

Comprehensive benefits package

Professional development opportunities

Flexible work arrangements

Job summary

Eacademy Sanofi is looking for a Senior Distinguished Scientist for Transgenic Model and Technology in Cambridge, MA. This pivotal role entails leading the Transgenic Model function globally, driving innovations in genome engineering, and overseeing model development to accelerate drug discovery.

The ideal candidate will possess a Ph.D. in Molecular Biology with extensive experience in transgenic technologies, and will excel in strategic thinking and interdisciplinary collaboration across therapeutic areas. A competitive compensation package and the opportunity to influence cutting-edge research await.

Qualifications

• Ph.D. degree is required.
• 5+ years of industry experience preferred.
• Proven track record in scientific leadership.

Responsibilities

• Lead genome engineering techniques for model development.
• Drive project management and resource allocation.
• Foster innovation through AI and digital technologies.

Skills

Transgenesis

CRISPR/Cas technology

Mouse genetics

Project management

AI integration

Education

Ph.D. in Molecular Biology, Genetics, Developmental Biology

Tools

CRISPR/Cas9

Gene editing tools

Job description

Job title:

Senior Distinguished Scientist for Transgenic Model and Technology

Location:

Cambridge, MA

About the job

The Translational In Vivo Models (TIM) department within Sanofi's R&D is seeking an exceptional Senior Distinguished Scientist to lead our Transgenic Model & Technology (TMT) function globally. This strategic leadership role will drive innovation in genome engineering and genetically modified model development to accelerate drug discovery across all therapeutic divisions. As the Global Head of Transgenic Biology, you will ensure our organization remains at the forefront of technical developments in genome engineering, enabling breakthrough discoveries in immunology, immuno‑inflammation, rare diseases, neuroscience, and oncology. You will serve as a key scientific advisor and strategic thinker, shaping the direction of in‑vivo and preclinical research programs while championing the integration of emerging technologies — including AI and digital platforms — into transgenic science. This role is based in Cambridge, MA and is primarily office/lab-based with some scope for flexible remote working.

Key Responsibilities

• Lead and advance state‑of‑the‑art genome engineering techniques and mouse genetics applications for in‑vivo model development supporting discovery and developmental research.
• Apply personal expertise in transgenesis and CRISPR technology to devise and execute sophisticated experimental strategies for target validation, proof‑of‑concept, and efficacy studies.
• Identify, evaluate, and implement new technologies and innovations in transgenesis, CRISPR/Cas systems, and emerging genome engineering platforms.
• Serve as a strategic thinker and scientific advisor to research projects across therapeutic areas, providing expert guidance on in‑vivo and preclinical study design.
• Champion the integration of AI and digital technologies to enhance model design, data analysis, and predictive capabilities in transgenic research.
• Cover a broad scientific scope including immunology and immuno‑inflammation, rare diseases, neuroscience, molecular and immune‑oncology, and all areas of cell and molecular biology pertaining to immunology and immune‑oncology.
• Demonstrate strategic thinking and orientation in aligning transgenic capabilities with organizational research priorities and long‑term scientific goals.
• Lead and coordinate transversal teams and projects across multiple therapeutic divisions, sites, and external partners.
• Collaborate closely with the Head of Transgenic Division, drug discovery program leaders, cluster heads, and department heads to provide strategic scientific advice.
• Drive budget planning, forecasting, and financial management to optimize resource allocation and operational efficiency.
• Establish and maintain comprehensive project management frameworks ensuring full‑service delivery from model design through study‑ready animal production.
• Build and manage strategic relationships with model providers, CROs, and academic partners for development and delivery of genetically modified models.
• Negotiate and oversee license agreements and partnership contracts for model acquisition and technology access.
• Implement quality standards and continuous improvement initiatives to maintain operational excellence.
• Supervise, mentor, and develop staff members to build a high‑performing team at the forefront of transgenic science.
• Participate in talent management decisions including hiring, promotions, performance evaluations, and organizational development.
• Foster a culture of scientific excellence, innovation, collaboration, and continuous learning.

Minimum Education and Experience Required

• Ph.D. in Molecular Biology, Genetics, Developmental Biology, or a related discipline.
• Extensive post‑doctoral or industry experience in mouse molecular genetics and transgenic animal model development.
• Demonstrated track record of scientific leadership in an academic or pharmaceutical/biotech research environment.
• Minimum of 5 years of demonstrated, hands‑on experience performing this role.

Additional Qualifications

Technical Expertise

• Deep expertise in developing transgenic animal models, including engineering diverse genetic alleles using CRISPR/Cas9, Cas12, base editors, prime editors, and other advanced genome engineering systems.
• Comprehensive knowledge of both theoretical principles and practical methodologies required to lead a state‑of‑the‑art transgenic facility.
• Strong foundation in molecular biology, mouse genetics, embryology, and reproductive technologies.
• Experience across multiple therapeutic areas (immunology, oncology, rare diseases, neuroscience preferred).

Leadership & Strategic Capabilities

• Proven strategic thinking and orientation with ability to align scientific capabilities with business objectives.
• Demonstrated success leading transversal teams and managing complex, multi‑stakeholder projects across sites and functions.
• Established track record as a scientific thinker and advisor to in‑vivo and preclinical research programs.
• Experience identifying, evaluating, and implementing new technologies and innovations in a research setting.
• Familiarity with and application of AI and digital technologies in biological research, model design, and data analysis.

Professional Skills

• Exceptional project management skills with ability to oversee multiple concurrent initiatives.
• Strong contract negotiation and vendor management capabilities.
• Excellent budget planning, financial management, and resource allocation skills.
• Outstanding interpersonal and communication skills for effective collaboration across diverse, global stakeholders.
• Proven ability to work in matrix organizations and influence without direct authority.

Personal Attributes

• Self‑motivated with demonstrated ability to lead and thrive in collaborative team environments.
• Comfortable managing competing priorities and adapting to dynamic research needs.
• Commitment to scientific excellence, integrity, and ethical research practices.
• Passion for mentoring and developing scientific talent.
• Willingness to travel as part of this position.

What We Offer

• Opportunity to shape the future of transgenic technology at a global biopharmaceutical leader.
• Access to cutting‑edge technologies and resources across a world‑class R&D organization.
• Collaborative, innovative research environment spanning multiple therapeutic areas.
• Competitive compensation and comprehensive benefits package.
• Professional development and career growth opportunities.
• Flexible work arrangements supporting work‑life balance.

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future‑focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well‑crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits.

Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectionate or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in company employee benefit programs, and additional benefits information can be found here.