Senior Director Trial Optimization and Feasibility

Scorpion Therapeutics; West Chester (Chester County); On-site; USD 200,000 - 260,000; Full time

Benefits offered by this job

Comprehensive health insurance

401(k) with match

Paid Time Off

Life and Disability (company-paid)

Job summary

Scorpion Therapeutics, based in the United States, seeks a Senior Director, Head of Trial Optimization & Feasibility to govern sponsor-side feasibility and optimization across global trials. You will validate CRO assumptions, shape country/site strategies, and lead analytics to support enrollment and startup decisions.

The role emphasizes evidence-driven forecast integrity, collaboration with CROs, and integrating patient burden, DCT, digital health, and sustainability considerations into study

Qualifications

• 12+ years of global clinical development experience with trial optimization and feasibility leadership.
• Experience in global, outsourced trial environments; able to challenge and validate CRO enrollment assumptions.
• Bachelor’s degree.

Responsibilities

• Define sponsor-side evidence standards for CRO feasibility packages.
• Assess enrollment rates, screen failure assumptions, startup timelines, and country allocation logic.
• Lead structured challenge sessions with CRO partners; endorse projections or elevate unrealistic assumptions.

Skills

12+ years

Global trials

Trial optimization

Feasibility leadership

Education

Bachelor's degree

Job description

Senior Director, Head of Trial Optimization & Feasibility (TOF)

How You’ll Spend Your Day

• Establish and govern Teva’s sponsor-side trial optimization and feasibility capability.
• Validate CRO feasibility assumptions; develop evidence-based enrollment forecasts.
• Shape country and site strategies; lead protocol operability reviews to improve execution.
• Build internal feasibility analytics; challenge and endorse enrollment/startup assumptions.
• Incorporate patient burden, diversity, DCT, digital health, and sustainability considerations.
• Drive continuous improvement via projected vs. actual reconciliation across studies, countries, therapeutic areas, and CROs.

Your Skills and Experience

• 12+ years of global clinical development experience with trial optimization and feasibility leadership.
• Experience in global, complex, highly outsourced trial environments; able to challenge and validate CRO enrollment assumptions.
• Bachelor’s degree.

Responsibilities (Feasibility Governance & Validation)

• Define sponsor-side evidence standards for CRO feasibility packages.
• Assess enrollment rates, screen failure assumptions, startup timelines, and country allocation logic.
• Lead structured challenge sessions with CRO partners; endorse projections or elevate unrealistic assumptions.

Also Good to Have

• Experience in neuroscience and immunology (preferred).
• Advanced degree (scientific/engineering/supply chain preferred).

Benefits (selected)

• Comprehensive health insurance; 401(k) with match; Paid Time Off; company-paid Life and Disability.