Senior Director, Translational Medicine (Clinical)

SciPro; California (MO); Remote; USD 250,000 - 350,000; Full time

Job summary

A leading biopharmaceutical company is seeking a Senior Director of Translational Medicine to guide strategies linking early discovery with clinical development. This leadership role emphasizes collaboration with cross-functional teams to advance innovative therapies. Ideal candidates are experienced translational scientists with a significant track record in driving programs from IND through NDA/BLA.

Qualifications

• 12+ years of industry experience in translational medicine or clinical biomarker roles.
• Proven track record of successful NDA/BLA submissions.
• Strong understanding of biomarker validation and regulatory interactions.

Responsibilities

• Lead translational strategy across multiple programs from preclinical through late-stage development.
• Collaborate closely with cross-functional teams to drive data-informed decisions.
• Represent Translational Medicine in interactions with regulatory authorities and external collaborators.

Skills

Leadership

Communication

Translational Science Principles

Education

Ph.D., M.D., or M.D./Ph.D.

Job description

Senior Director, Translational Medicine (Clinical)

Senior Director, Translational Medicine (Clinical)

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Job Title: Senior Director, Translational Medicine

Location: Remote (U.S.-based) with occasional travel to California

Position Type: Full-Time

About the Role:

We are partnering with a well-funded, innovative biotech company advancing a pipeline of first- and best-in-class therapies through clinical development. As they continue to scale, they are seeking a Senior Director of Translational Medicine to serve as a critical link between early discovery and clinical development, guiding strategies that bring high-impact therapies to patients.

This is a high-visibility, cross-functional leadership role ideal for an accomplished translational scientist with a strong track record of driving programs from IND through NDA/BLA.

Key Responsibilities:

• Lead translational strategy across multiple programs from preclinical through late-stage development
• Serve as scientific lead for biomarker development, target engagement, PK/PD strategy, and patient stratification
• Collaborate closely with discovery biology, clinical development, regulatory, and commercial teams to drive data-informed decisions
• Interpret nonclinical and clinical data to inform trial design and regulatory filings
• Represent Translational Medicine in interactions with regulatory authorities, key opinion leaders, and external collaborators
• Provide scientific oversight for CROs, academic partnerships, and biomarker assay development
• Contribute to authoring and reviewing regulatory documents including INDs, NDAs, and BLAs

Required Qualifications:

• Ph.D., M.D., or M.D./Ph.D. in Neuroscience, Immunology, Cardiovascular, or Metabolic Disease-related field
• 12+ years of industry experience, including significant leadership in translational medicine or clinical biomarker roles
• Proven track record of contributing to multiple successful NDA/BLA submissions
• Proven experience interacting with the FDA from a preclinical/translational standpoint
• Strong understanding of translational science principles including biomarker validation, PK/PD modeling, and early clinical study design
• Experience working across therapeutic areas with a focus on mechanistic and data-driven approaches
• Exceptional communication and leadership skills with ability to collaborate across disciplines

Seniority level

• Seniority level

  Director

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research

• Industries

  Pharmaceutical Manufacturing and Biotechnology Research

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