Senior Director, Supply Chain & Logistics

X4 Pharmaceuticals INC; Boston (MA); Hybrid; USD 250,000 - 280,000; Full time

Job summary

X4 Pharmaceuticals is headquartered in Boston, MA, and is seeking a Senior Director of Supply Chain & Logistics to drive end-to-end clinical and commercial supply. The role emphasizes risk management, cross-functional collaboration, and strategic planning to ensure uninterrupted patient access.

Based in Boston with a flexible hybrid work model, the position requires a minimum of 12 years in pharma supply chain, strong leadership, and proficiency with ERP systems and MS Office.

Qualifications

• 12+ years of clinical and/or commercial manufacturing, supply chain and logistics experience in the pharmaceutical industry
• Bachelor's Degree in a relevant field (see education)
• Travel 20% internationally and domestically
• Experience with ERP systems
• Proficient in Microsoft Office applications (Excel, PowerPoint, Outlook)

Responsibilities

• Ensure global clinical and commercial supply continuity and risk management.
• Lead cross-functional partnerships with Quality, Regulatory, Technical, and Clinical teams.
• Forecast initial and ongoing clinical drug supply needs and demand assumptions; ensure startup and distribution to sites.
• Lead Integrated Business Planning to monitor demand and plan supply.
• Plan activities related to packaging, labeling, shipping licenses, cold chain, distribution, procurement, storage, and inventory control.
• Coordinate with Third Party Logistics, Finance, and Accounting for invoices and carrying costs.
• Manage and maintain commercial serialization across territories.
• Develop SOPs to support global supply chain processes.
• Coordinate artwork and packaging design with external suppliers for all markets.
• Manage relationships with multiple distribution partners and cross-functional teams.
• Support EAP/PTA strategy across indications and territories.
• Manage budget, purchase orders, and invoices for supply chain.

Skills

Supply chain data analysis

Microsoft Office

ERP systems

Education

Bachelor's degree in Pharmaceutics, Pharmacy, Chemical Engineering, Biotechnology Engineering, Chemistry, Biochemistry, or Biology

Tools

ERPs

Job description

If you are unable to complete this application due to a disability, contact this employer to ask for an accommodation or an alternative application process.

Senior Director, Supply Chain & Logistics

Full Time Boston, MA, US

3 days ago Requisition ID: 1174

Salary Range: $250,000.00 To $280,000.00 Annually

Do you have the passion and commitment to join a team whose mission is to develop treatments that have a clear and profound impact on people with rare diseases of the immune system? Does it excite you to be a part of a company developing potential new treatments that could dramatically improve the lives of people with limited to no treatment options? X4 is an exceptional place to work, with team members who are dedicated to patients, partners in the medical community and each other.

X4 Pharmaceuticals is a commercial-stage biopharmaceutical company committed to transforming the treatment of rare hematologic and immune disorders through innovative, patient-focused therapies. Building on its expertise in CXCR4 biology and the successful commercialization of XOLREMDI® (mavorixafor), X4 is advancing a global Phase 3 clinical program evaluating mavorixafor for chronic neutropenia, a group of rare disorders characterized by persistently low neutrophil counts and an increased risk of serious infections.

We recognize that developing innovative, new medicines is challenging, but we embrace this challenge to truly make progress for patients each day. If you feel you would be a good fit for X4, we invite you to join the team.

At X4 you will find…

• A team that values grit and innovative science.
• The opportunity to leverage your knowledge of Supply Chain to support our innovative science and allow you to have a major impact on our mission to support our patients.
• A collegial environment with a team-based approach, where our mission drives our values, behaviors, and creativity.

Your Responsibilities:

• Responsible for global clinicaland commercialsupply continuity and risk management processes, owning and assessing supply chain plans and inventories.
• Drive and lead cross-functional partnerships with Quality, Regulatory, Technical, and Clinical partners
• Collaborate with Clinical Operations to forecast initial and ongoing clinical drug supply needs and demand assumptions (enrollment rates, number of sites, number of countries, etc.) and assure successful start-up of and distribution to clinical sites.
• Lead Integrated Business Process (IBP) to monitor clinical and commercial demand and plan supply accordingly; evolve process, as needed, to meet current business needs.
• Plan and implement activities related toclinical andcommercial supply chain, customs clearance, cost management, storage, warehousing, distribution, procurement, logistics, forecast, inventory control, data management, and production planning.
• Ensure the availability of commercial product inventory in the supply chain, as scheduled, and the maintenance of inventory at minimum acceptable levels and cost, applying risk-based review of the supply chain.
• Coordinate with Third Party Logistics/Finance/Accounting for invoices and inventory carrying costs.
• Manage and maintain commercial serialization across all territories.
• Partner with Quality Assurance to enable global acceptance of clinical & commercial material and ensure compliance across all stages of supply chain management.
• Manage and oversee development of SOPs and necessary processes and procedures to support global supply chain.
• Develop and manage plans forclinical and commercialpackaging/labeling processes, shipping authorization, import/export licenses, cold chain global distribution, etc. to ensure continuity of supply
• Coordinate artwork and packaging design for printed packaging components through external suppliers for all markets
• Manage supply and relationship with multiple distribution partners (global partnerships utilizing both clinical and commercial material).
• Work as part of a cross-functional team to develop EAP/PTA strategy across all indications and territories.
• Manage budget, contractual obligations, purchase orders, and invoices for supply chain

What You Will Bring:

• Minimum of 12 years of clinical and/or commercial manufacturing, supply chain and logistics work experience in the pharmaceutical industry
• Minimum Bachelor's Degree in Pharmaceutics, Pharmacy, Chemical Engineering, Biotechnology Engineering, Chemistry, Biochemistry, Biology
• National and international travel will be required (20%)
• Commercial Pharmaceutical Manufacturing, Supply Chain, Logistics
• Managing/interacting with Third Party Logistics, Client Services, Wholesale and Retail Warehouses, Customers, Vendors, Finance, Accounting
• Supply Chain Data Analysis
• Experience with ERPs
• Skilled in Microsoft Office, including Outlook, Excel, and PowerPoint

This position is based in Boston, MA, and offers a flexible hybrid work model with a minimum of 2 days/week in the office.

We encourage you to learn more about X4 Pharmaceuticals.

X4 Pharmaceuticals is an Equal Opportunity, and All qualified candidates will receive consideration without regard to race, color, creed, religion, national origin, age, ancestry, nationality, marital, domestic partnership or civil union status, sex, gender identity or expression, sexual orientation, disability, veteran status, violence victim status or any other characteristic protected by law.

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