Senior Director of Clinical Science, Lung & Head & Neck

Regulatory Jobs; Rahway (NJ); Hybrid; USD 210,000 - 331,000; Full time

Job summary

Merck & Co., Inc. in Rahway, NJ is seeking a Senior Director of Clinical Science to provide strategic leadership across lung and head & neck programs, guiding study design, evidence generation, and regulatory strategy.

The role partners with Clinical Directors and senior leaders to shape development decisions and ensure scientific excellence. The position entails oversight of medical monitoring, interpretation of complex data, and integration of external data and AI-enabled approaches.

Qualifications

• Advanced healthcare or scientific degree (e.g., PhD, PharmD) with 8+ years of pharmaceutical, clinical drug development, and/or medical field experience preferred.
• Master’s degree in life sciences with 12+ years of pharmaceutical, clinical drug development, and/or medical field experience preferred.
• Bachelor’s degree in life sciences with 15+ years pharmaceutical, clinical drug development, and/or medical field experience preferred.

Responsibilities

• Provide strategic scientific leadership across programs, assets, or disease areas, ensuring quality and consistency of Clinical Science approaches.
• Shape the development and evolution of Clinical Development Plans and set strategic direction for study design.
• Provide oversight of medical monitoring and medical data review approaches and guide interpretation of complex clinical data across programs.
• Integrate clinical evidence, therapeutic-area science, emerging external data, and competitive insights to shape development strategy across programs.
• Provide strategic oversight and clinical guidance for key regulatory documents, Health Authority interactions, and other major development activities.
• Shape governance strategy and communicate scientific development opportunities to senior leaders.
• Shape scientific publication and external engagement strategies and develop strategic relationships with investigators and key opinion leaders.
• Provide strategic oversight of clinical/scientific quality, risk management, and audit and inspection readiness across areas of responsibility.
• Shape digital and AI-enabled Clinical Science approaches, identify high-value use cases, and drive scalable adoption across programs.
• Shape Clinical Science standards, leading practices, and ways of working across programs or disease areas.
• Develop Clinical Science talent and organizational capabilities through scientific leadership, coaching, mentoring, and sponsorship.
• May lead a large Clinical Science team.

Skills

Clinical Development

Clinical Leadership

Clinical Product Development

Clinical Research

Clinical Research Management

Clinical Sciences

Clinical Trial Development

Clinical Trial Management

Decision Making

Drug Development

Education

Advanced healthcare or scientific degree (e.g., PhD, PharmD)

Master’s degree in life sciences

Bachelor’s degree in life sciences

Job description

Merck & Co., Inc. in Rahway, NJ is seeking a Senior Director of Clinical Science to provide strategic leadership across lung and head & neck programs, guiding study design, evidence generation, and regulatory strategy.

The role partners with Clinical Directors and senior leaders to shape development decisions and ensure scientific excellence. The position entails oversight of medical monitoring, interpretation of complex data, and integration of external data and AI-enabled approaches.