Senior Director, ICX Data, Analytics & AI

Vertex Pharmaceuticals Inc (US); United States; Hybrid; USD 228,000 - 342,000; Full time

Job summary

Vertex Pharmaceuticals Inc. is seeking a Sr. Director, ICX Data, Analytics & AI to lead the intelligence engine powering Vertex’s integrated customer experience.

You will set the strategy for data and AI capabilities, oversee the intelligence layer, and partner with Legal, Medical, Regulatory, and external vendors to deliver compliant, scalable, and commercially impactful solutions. You will build and lead a high-performing team, drive data governance and Responsible AI practices, and align

Qualifications

• Experience leading data, analytics, AI/ML initiatives with measurable outcomes.
• Ability to translate data capabilities into commercial value.
• Experience in regulated industries preferred.

Responsibilities

• Set and execute ICX data and AI strategy aligned to commercial priorities.
• Lead end-to-end intelligence layer incl. data products, models, decisioning, and AI agents.
• Build and scale a team and manage vendor ecosystem.
• Ensure compliance, governance, and responsible AI practices.

Skills

Data strategy

AI/ML

Analytical leadership

Cross-functional collaboration

Executive communication

Vendor management

Governance

Education

Bachelor's degree

Advanced degree preferred

Job description

Job Summary

Job Description General Summary: The Sr. Director, ICX Data, Analytics & AI leads the intelligence engine behind Vertex’s integrated customer experience. This role is accountable for the data, analytics, models, decisioning, and AI agents that power precision engagement today and enable Vertex’s broader agentic capabilities over time. The role sets the strategic direction for ICX data and AI capabilities; oversees the intelligence layer across the customer experience; and partners with Digital Technology & Engineering/Data Science Solutions (DTE/DSS), Commercial, Legal, Medical, Regulatory, and external vendors to deliver compliant, scalable, and commercially impactful solutions.

Key Duties and Responsibilities

Set and execute the data, analytics, AI, and agentic strategy and roadmap for the ICX organization, aligned to commercial priorities and enterprise technology direction. Own build, buy, and partner decisions, including investment cases, capability roadmaps, vendor selection, and value realization. Lead the end-to-end intelligence layer supporting the integrated customer experience, including data products, customer analytics, predictive models, next-best-action decisioning, and AI agent portfolio. Establish and scale AI agents and AI/ML capabilities that improve precision engagement, enable orchestration across channels, and advance Vertex’s agentic maturity. Own enterprise measurement and the commercial closed loop—turning customer engagement, channel, and performance signals into actionable insights and measurable business results. Define and lead ICX data strategy, data governance, data quality, and Responsible AI practices. Serve as the senior ICX accountability point with Legal, Medical, Regulatory, Privacy, and Compliance partners to ensure AI and data solutions are compliant, transparent, defensible, and fit for use. Partner with DTE/DSS on shared infrastructure, data foundations, engineering standards, integration, model operations, and scalable delivery. Build, lead, and develop a high-performing team of approximately 9 direct reports spanning data strategy, analytics, data science, AI, measurement, and decision science. Develop the internal talent bench and external vendor ecosystem required to deliver strategic capabilities at speed and scale. Champion AI, data, and digital literacy across the Commercial organization to drive adoption, responsible use, and return on investment. Partner closely with ICX Platforms and other cross-functional stakeholders to connect intelligence, activation, measurement, and customer experience outcomes.

Knowledge and Skills

Data and AI strategy Agentic AI and intelligent decisioning Commercial analytics and measurement Responsible AI and data governance Digital customer experience Talent and vendor ecosystem leadership Cross-functional influence and executive communication Value realization and commercial impact

Education and Experience

Bachelor’s degree required; advanced degree in data science, analytics, computer science, engineering, business, or a related field preferred. Significant leadership experience in data, analytics, AI/ML, decision science, digital strategy, or customer experience. Demonstrated experience translating data and AI capabilities into measurable commercial, customer, or business outcomes. Experience developing and operationalizing data products, predictive models, next-best-action or decisioning capabilities, and AI/agentic solutions. Strong understanding of data governance, data quality, Responsible AI, model risk, privacy, and compliance requirements. Proven ability to lead complex build, buy, and partner decisions and manage strategic technology or analytics vendors. Experience leading high-performing, multidisciplinary teams and influencing senior stakeholders in a matrixed organization. Experience in biopharma, healthcare, or another highly regulated industry strongly preferred. At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision‑making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range

Pay Range: $228,000 - $342,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market‑leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week‑long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation

Flex Designation: Hybrid-Eligible Or On‑Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On‑Site: work five days per week on‑site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E‑Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [e-mail]. Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases and conditions. The company has approved therapies for cystic fibrosis, sickle cell disease, transfusion‑dependent beta thalassemia, acute pain and acromegaly, and it continues to advance clinical and research programs in these areas. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including IgA nephropathy, neuropathic pain, APOL1‑mediated kidney disease, primary membranous nephropathy, congenital adrenal hyperplasia, ACTH‑dependent Cushing's syndrome, autosomal dominant polycystic kidney disease, type 1 diabetes, generalized myasthenia gravis, and myotonic dystrophy type 1. Vertex was founded in 1989 and has its global headquarters in Boston, with international headquarters in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 16 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on LinkedIn, Facebook, Instagram, YouTube, and X. We believe our culture is one of Vertex’s greatest strengths and a key enabler of our ability to deliver transformative medicines for patients who need them. Rooted in innovation, purpose and collaboration, our culture empowers people to take smart risks, challenge conventional thinking and do their best work. The diversity of our people is central to that culture. By bringing together individuals with different backgrounds, experiences and perspectives, we foster an environment where new ideas thrive, better decisions are made and breakthrough innovation is possible. We are committed to creating a workplace where everyone feels valued, included and connected to our shared mission, because we know that our unique culture and the collective strength of our people are what set Vertex apart.