Senior Director, GU Oncology Clinical Science

Merck & Co.; Boston (MA); Hybrid; USD 210,000 - 331,000; Full time

Job summary

Merck & Co., Inc. in Rahway, NJ, seeks a Senior Director, Clinical Science for Genitourinary Oncology to lead strategic Clinical Science across multiple GU cancer programs, guiding development planning and standardizing scientific practices.

This senior role collaborates with cross-functional teams to align endpoints, biomarker strategies, and governance reviews, while mentoring Clinical Scientists within a matrix organization.

Qualifications

• Significant experience in Clinical Development, Clinical Science, clinical drug development, or a related function.
• Demonstrated experience providing Clinical Science leadership across multiple studies, programs, or assets.
• Deep therapeutic area expertise, including strong understanding of disease biology, current and emerging treatment landscape, clinically relevant endpoints, and key scientific considerations affecting development.
• Strong understanding of clinical trial design, clinical development strategy, clinical data review, and interpretation of oncology data.
• Experience contributing to disease area strategy, portfolio discussions, or cross-program planning.

Responsibilities

• Provide strategic Clinical Science leadership across the disease area, including multiple studies, programs, and assets.
• Contribute to disease area strategy by providing Clinical Science input on development opportunities, scientific considerations, portfolio risks, and implications of emerging internal and external data.
• Partner with Section Heads, Asset Leads, Program Development Team Leads, and cross-functional leaders to support alignment of Clinical Science activities with broader program and disease area objectives.
• Apply expert knowledge of therapeutic focus, disease biology, treatment landscape, and clinically meaningful endpoints to inform study planning, data interpretation, and issue resolution.
• Support cross-study and cross-asset integration of scientific insights to inform development decisions.

Skills

Clinical Development

Clinical Research

Clinical Research Management

Clinical Sciences

Clinical Trial Planning

Oncology

People Leadership

Study Design

Therapeutic Knowledge

Trial Design

Education

Advanced degree (PhD, PharmD, or equivalent)

Master's degree in life sciences

Bachelor's degree in life sciences

Job description

Merck & Co., Inc. in Rahway, NJ, seeks a Senior Director, Clinical Science for Genitourinary Oncology to lead strategic Clinical Science across multiple GU cancer programs, guiding development planning and standardizing scientific practices.

This senior role collaborates with cross-functional teams to align endpoints, biomarker strategies, and governance reviews, while mentoring Clinical Scientists within a matrix organization.