Senior Director, Core Technology Architect

Vertex Pharmaceuticals; Boston (MA); Hybrid; USD 228,000 - 342,000; Full time

Benefits offered by this job

Hybrid-eligible

Annual bonus

Equity awards

Comprehensive benefits

Job summary

Vertex Pharmaceuticals seeks a Senior Director, Solution Architect – Core Technology to lead an integrated architecture strategy across cloud, collaboration, and end-user computing in a global, regulated biopharma environment.

The role creates foundational architecture, partners with Information Security, and aligns infrastructure with enterprise risk and regulatory requirements. Hybrid/On-site work as part of flex policy is offered.

Qualifications

• Proven leadership in enterprise architecture across multiple domains.
• Experience with Azure-first cloud strategy and hybrid environments.
• Knowledge of GxP, regulatory, and security requirements.

Responsibilities

• Define end-to-end solution architecture for Core Technology.
• Partner with Information Security to co-architect cybersecurity platforms.
• Establish governance, standards, and reference architectures across domains.
• Drive AI enablement within Microsoft and Azure AI ecosystems.

Skills

Azure architecture

AWS

Microsoft 365

Security architecture

GxP/compliance

End-user computing

AI in enterprise

Enterprise networking

Tools

ServiceNow

Zoom

Teams Rooms

Job description

Job DescriptionVertex is seeking a Senior Director, Solution Architect – Core Technology to serve as a senior individual contributor responsible for defining and driving an integrated architecture strategy across infrastructure and collaboration platforms in a global, GxP-regulated biopharma environment.This leader will establish the foundational architecture function within Core Technology and partner closely with domain leaders across cloud, network, collaboration, end-user computing, workplace technology, and service management. This role will ensure that enterprise technologies are cohesive, scalable, secure, and compliant, while helping shape a unified AI and digital workplace strategy across Microsoft 365, cloud platforms, and end-user environments.This role will partner closely with Information Security to co-architect cybersecurity capabilities across the Core Technology ecosystem and drive alignment between infrastructure, collaboration, and security architecture strategies to ensure secure, scalable, and compliant technology solutions.Key Duties and Responsibilities:Enterprise Integration & Architecture StrategyDefine and drive end-to-end solution architecture across Core Technology domains, including:Cloud platforms, with an Azure-first strategy and existing AWS footprintMicrosoft 365 ecosystem, including Teams, Exchange, SharePoint, and Copilot enablementEnterprise network services, including connectivity, SD-WAN, and global infrastructureData center and hybrid hosting environmentsEnd-user computing across Windows, Mac, and mobilityConference room and workplace collaboration technologies, including Zoom and Teams RoomsITSM and service experience platforms, including ServiceNowPartner with Information Security to co-architect and integrate cybersecurity platforms and controls across cloud, network, workplace, collaboration, and end-user computing domains, ensuring alignment with Core Technology reference architecture, operational models, and enterprise risk requirements.Partner with Information Security to establish shared architecture principles, technology standards, integration patterns, and governance processes that align infrastructure, collaboration, and security architecture across the enterpriseCreate reference architectures, design standards, and integration patterns across technology domainsEliminate silos and ensure interoperability across Core Technology servicesDrive scalable and sustainable architectural approaches that support global business needsAI & Digital Workplace EnablementLead Core Technology architecture strategy to enable enterprise AI capabilitiesSupport AI enablement within:The Microsoft ecosystem, including Copilot, Microsoft 365, and Azure AIEnd-user productivity and collaboration platformsEnsure AI-related solutions are securely integrated across infrastructure layersPartner with Security and Data teams to align AI architecture with governance, privacy, and regulatory expectationsHelp shape a seamless and secure digital workplace experience for employees globallyArchitecture Governance & StandardsPartner with Information Security to establish shared architecture principles, technology standards, integration patterns, and governance processes that align infrastructure, collaboration, and security architectures across the enterpriseEstablish architecture governance processes, including:Design reviewsTechnology standardsException managementServe as the central point of accountability for cross-domain architectural decisionsEnsure alignment with GxP, regulatory, compliance, and security requirementsDrive lifecycle management, rationalization, and modernization of Core Technology platformsCross-Functional Leadership & InfluenceOperate as a peer to Directors across Network, Cloud, EUC, Collaboration, and related domains.Serve as the primary Core Technology architecture partner to Information Security, driving joint architecture reviews, technology evaluations, integration decisions, and long-term platform strategy.Influence technical direction across a federated organization without direct authorityPartner closely with Information Security, Data Services, and Application teams to define and maintain a unified infrastructure, collaboration, and security architecture strategy and roadmap.Act as a trusted advisor to senior DTE leadership on technology strategy, investments, and roadmap decisionsBalance strategic vision with practical execution to accelerate business valueVendor & Partner AlignmentShape architecture strategy in partnership with key vendors and service providers, including:Microsoft (Azure, M365)Cisco, Palo Alto, Verizon, AT&T (network and security)Zoom (collaboration)ServiceNow (ITSM)Accenture (managed services and operations)Lenovo, Dell, Apple (end-user computing)Ensure third-party solutions align with enterprise architecture standards and long-term technology strategySupport effective vendor collaboration to deliver secure, compliant, and high-performing servicesOperational AlignmentEnsure solutions are designed for operability in partnership with outsourced operations teamsDrive consistency between architecture and service delivery models, including Service Desk and Deskside SupportImprove end-user experience, supportability, and reliability through cohesive technical designStrengthen alignment between architecture, engineering, and operationsKnowledge and Skills:Azure architecture and cloud services - AWS cloud environments - Microsoft 365 ecosystem - Microsoft Teams – Exchange - SharePoint - Microsoft Copilot - Azure AI - Enterprise networking and infrastructure - SD-WANSecurity architecture alignment and experience co-architecting cybersecurity technologies including identity, endpoint protection, network security, zero-trust, and cloud security solutions.Data center and hybrid hostingEnd-user computing across Windows , Mac , and mobility platformsCollaboration technologies including Zoom and Teams RoomsServiceNow and ITSM platformsArchitecture governance and standards developmentReference architecture and integration pattern designTechnology lifecycle management and rationalizationPreferred SkillsExperience enabling enterprise AI solutions in a regulated environmentFamiliarity with digital workplace transformation initiativesBackground in hybrid infrastructure and global collaboration ecosystemsKnowledge of service delivery operating models and managed services integrationExperience improving interoperability across infrastructure, workplace, and support platformsStrong understanding of compliance, governance, and secure-by-design architecture principlesEducation and Experience:12–15+ years of experience in IT infrastructure and workplace technologiesProven experience in solution architecture or enterprise architecture leadership rolesExperience operating in complex, global enterprise environmentsDemonstrated success working across multiple infrastructure domains simultaneouslyExperience in GxP-regulated environments such as biotechnology, pharmaceuticals, or healthcare strongly preferredDemonstrated ability to lead through influence in a federated organizationStrong executive presence with excellent communication and stakeholder management skillsAbility to translate complex technical concepts into clear business-aligned recommendationsProven ability to balance strategic architecture with pragmatic executionExperience collaborating with global vendors, strategic partners, and managed service providersPay Range:$228,000 - $342,000Disclosure Statement:The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.Flex Designation:Hybrid-Eligible Or On-Site EligibleFlex Eligibility Status:In this Hybrid-Eligible role, you can choose to be designated as:1. Hybrid : work remotely up to two days per week; or select2. On-Site : work five days per week on-site with ad hoc flexibility.Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.#LI-HybridCompany InformationVertex is a global biotechnology company that invests in scientific innovation.Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [e-mail]