Senior Director, Commercial Infrastructure & Operations

Apnimed; Cambridge (MA); Remote; USD 270,000 - 294,000; Full time

Benefits offered by this job

401(k) with company match

Generous time off for vacation

Generous healthcare benefits

Flexible working environment

Motivated and experienced team

Winner of 2024 and 2025 Boston Best P­

Job summary

Apnimed, a Boston-area biopharmaceutical company focused on sleep apnea, seeks a Sr. Director to build and run the commercial operations infrastructure—licensing, P2P programs, congresses and field meetings, content submission, and literature distribution.

You will lead cross‑functional partnerships to scale the business, identify AI and automations to reduce manual work, and position the organization for the potential commercialization of AD109, a first‑in‑class pharmaceutical treatment for

Qualifications

• Bachelor's degree required; advanced degree preferred.
• 12+ years of progressive commercial operations experience.
• Experience in field licensing, speaker/P2P programs, events logistics.
• Experience managing promotional content submissions & MLR workflows.
• Experience managing 3PL or distribution vendor relationships.
• Knowledge of PhRMA Code, Sunshine Act & speaker program compliance.
• Familiarity with AI and automation for operations.
• Vendor management & contract negotiation skills.
• Excellent organizational and project management skills.
• Excellent verbal and written communication.
• Proficiency in MS Word, PowerPoint; Adobe Acrobat.

Responsibilities

• Direct Field State Licensing and renewal monitoring.
• Lead P2P Operations with logistics, compliance checks, and budgeting.
• Drive Congresses, Meetings & Events planning and execution.
• Oversee Commercial Content Submission workflows and MLR timing.
• Oversee Sample & Literature Operations including forecasting.
• Partner cross-functionally to scale operational infrastructure.
• Coordinate external vendors for licensing, events, content, and distribution.

Skills

Vendor management

Project management

Communication skills

Organizational skills

Contract negotiation

Education

Bachelor's degree; advanced degree preferred

Tools

MS Word

PowerPoint

Adobe Acrobat Pro

Job description

Apnimed is a rapidly growing pharmaceutical company working to transform the treatment of sleep apnea based on a simple idea - patients with obstructive sleep apnea (OSA) could benefit from treatment with a safe and effective oral medication dosed once daily at bedtime. Our lead development program, AD109, targets the neurologic control of upper airway muscles to maintain an open airway during sleep. Apnimed is committed to innovation, as well as state-of-the-art advancements in sleep medicine, which is leading to the development of a portfolio of novel pharmacologic therapies for sleep apnea and related disorders.

Recognized by the Boston Business Journal as one of the Best Places to Work in both 2024 and 2025, we are continuing to grow and build the foundational operations that enable our employees and our mission to thrive.

Summary:

The Sr. Director, Commercial Infrastructure & Operations reports to the VP, Commercial Operations and is responsible for the operational infrastructure and logistics that keep Apnimed's commercial organization running day to day, spanning field state licensing, peer-to-peer (P2P) program operations, congresses and field meetings, commercial content submission, and sample and literature operations. The successful candidate will also play a key role in identifying where AI and automation can meaningfully reduce manual work and improve accuracy across these programs. This is an exciting opportunity to build durable, well-run commercial infrastructure right the first time and shape how it runs for years to come as Apnimed prepares for the potential commercialization of AD109, an investigational therapy, and to be at the forefront of a major paradigm shift in the treatment of sleep apnea from medical devices and surgery to a first in class pharmaceutical treatment.

The expected annual base salary range for this role is $270,000.00 to $294,000.00. Final compensation will depend on the selected candidate's level, education and relevant experience.

Key Job Duties include, but are not limited to:

• Direct Field State Licensing, maintaining state licensing and registration requirements for the field organization, including renewal monitoring and compliance tracking to prevent lapses.
• Lead P2P Operations, overseeing execution of peer-to-peer and speaker programs, including logistics, HCP compliance checks, meal and spend caps, attendance capture, and closeout, in partnership with HCP Marketing, which owns P2P program strategy, planning, and budget allocation.
• Drive Congresses, Meetings & Events, planning and executing commercial congress presence and field meetings, including logistics planning and vendor/budget optimization.
• Oversee Commercial Content Submission, ensuring promotional content submission workflows, routing, and tracking accelerate MLR review cycle times (delivered through the Associate Director, Field Distribution & Licensing Operations).
• Oversee Sample & Literature Operations, coordinating sample and medical literature distribution and fulfillment, including demand forecasting and inventory management.
• Partner cross-functionally across the commercial organization to ensure operational infrastructure supports every team's needs as the business scales.
• Coordinate external vendors and partners supporting field state licensing, speaker program and event logistics, content submission, and sample/literature distribution.

Apnimed is a rapidly growing pharmaceutical company working to transform the treatment of sleep apnea based on a simple idea - patients with obstructive sleep apnea (OSA) could benefit from treatment with a safe and effective oral medication dosed once daily at bedtime. Our lead development program, AD109, targets the neurologic control of upper airway muscles to maintain an open airway during sleep. Apnimed is committed to innovation, as well as state-of-the-art advancements in sleep medicine, which is leading to the development of a portfolio of novel pharmacologic therapies for sleep apnea and related disorders.

Recognized by the Boston Business Journal as one of the Best Places to Work in both 2024 and 2025, we are continuing to grow and build the foundational operations that enable our employees and our mission to thrive.

Summary:

The Sr. Director, Commercial Infrastructure & Operations reports to the VP, Commercial Operations and is responsible for the operational infrastructure and logistics that keep Apnimed's commercial organization running day to day, spanning field state licensing, peer-to-peer (P2P) program operations, congresses and field meetings, commercial content submission, and sample and literature operations. The successful candidate will also play a key role in identifying where AI and automation can meaningfully reduce manual work and improve accuracy across these programs. This is an exciting opportunity to build durable, well-run commercial infrastructure right the first time and shape how it runs for years to come as Apnimed prepares for the potential commercialization of AD109, an investigational therapy, and to be at the forefront of a major paradigm shift in the treatment of sleep apnea from medical devices and surgery to a first in class pharmaceutical treatment.

The expected annual base salary range for this role is $270,000.00 to $294,000.00. Final compensation will depend on the selected candidate's level, education and relevant experience.

Key Job Duties include, but are not limited to:

• Direct Field State Licensing, maintaining state licensing and registration requirements for the field organization, including renewal monitoring and compliance tracking to prevent lapses.
• Lead P2P Operations, overseeing execution of peer-to-peer and speaker programs, including logistics, HCP compliance checks, meal and spend caps, attendance capture, and closeout, in partnership with HCP Marketing, which owns P2P program strategy, planning, and budget allocation.
• Drive Congresses, Meetings & Events, planning and executing commercial congress presence and field meetings, including logistics planning and vendor/budget optimization.
• Oversee Commercial Content Submission, ensuring promotional content submission workflows, routing, and tracking accelerate MLR review cycle times (delivered through the Associate Director, Field Distribution & Licensing Operations).
• Oversee Sample & Literature Operations, coordinating sample and medical literature distribution and fulfillment, including demand forecasting and inventory management.
• Partner cross-functionally across the commercial organization to ensure operational infrastructure supports every team's needs as the business scales.
• Coordinate external vendors and partners supporting field state licensing, speaker program and event logistics, content submission, and sample/literature distribution.

Requirements

• Bachelor's degree required; advanced degree preferred.
• 12+ years of progressive commercial operations experience in the biopharmaceutical industry, with direct experience managing field state licensing/registration, speaker or P2P program operations, event logistics, or sample/literature distribution.
• Experience managing promotional content submission processes and MLR review workflows.
• Experience managing third-party logistics (3PL) or distribution vendor relationships for sample and literature fulfillment.
• Working knowledge of the PhRMA Code, Sunshine Act transparency reporting, and speaker program compliance.
• Familiarity applying AI and automation tools (e.g., license/compliance tracking, speaker program spend monitoring, demand forecasting, content routing) to operational and logistics functions.
• Strong vendor management and contract negotiation skills.
• Excellent organizational and project management skills, with the ability to manage multiple concurrent logistics programs.
• Ability to manage simultaneous priorities and changing deadlines.
• Excellent oral and written communication skills.
• Proficiency in the use of MS Word, PowerPoint; experience with Adobe Acrobat Professional.

Benefits

• 401(k) with company match
• Generous time off for vacation
• Generous healthcare benefits
• Flexible working environment
• Motivated and experienced team
• Winner of 2024 and 2025 Boston Business Journal Best Places to Work

Location and Other Information:

• Apnimed is a publicly licensed company based in Cambridge, MA; we are generally virtual and specific location within the US is not critical.
• We are a small growing Company with an inclusive environment.
• Must be able to travel as necessary.
• Apnimed is an EEO employer committed to an exciting, diverse, and enriching work environment.
• Please visit us at www.apnimed.com to learn more about our work with Obstructive Sleep Apnea.