Senior Director, Clinical Science, Oncology Early Development

Regulatory Toolkit; Rahway (NJ); In loco; USD 180.000 - 260.000; Tempo pieno

Descrizione del lavoro

Senior Director, Clinical Science, Oncology Early Development provides strategic leadership for novel assets from candidate transition through first-in-human development and clinical proof-of-concept. This role shapes development plans, strengthens scientific rigor, and enables objective, data-driven decisions across the early oncology portfolio.

It integrates pharmacokinetic/pharmacodynamic data, biomarker strategy, safety, and external evidence to inform dose escalation, cohort expansion, and

Descrizione del lavoro

Job Description

The Senior Director, Clinical Science, Oncology Early Development is responsible for providing strategic Clinical Science leadership for novel assets from candidate transition through first-in-human development and clinical clinical proof-of-concept. Reporting to the Executive Director, this role contributes to the early development and scientific platform strategy by applying deep expertise in early-phase oncology, translational medicine, biomarker strategy, and first-in-human (FIH) trail design to shape development plans, strengthen scientific rigor and enable objective, data-driven decision-making across the early oncology portfolio.

The Senior Director integrates emerging clinical, pharmacokinetic, pharmacodynamic, biomarker, safety, and external scientific evidence to inform indication strategy, dose escalation and optimization, cohort expansion, and proof-of-concept assessments. The role partners closely with Section Heads, Asset Leads, Early Program Development Team Leads, study teams, and cross-functional leaders to guide study design, data interpretation, issue resolution, and program decisions.