Senior Director, Cardiovascular Clinical Development (EDG-2025008)

Edgewise Therapeutics; Massachusetts; On-site; USD 253,000 - 299,000; Full time

Job summary

A leading biopharmaceutical company is searching for a Senior Director of Cardiovascular Clinical Development who will contribute to the development of innovative therapies for muscle diseases. The successful candidate will act as a strategic partner in clinical strategy and operations, ensuring regulatory compliance and collaboration with cross-functional teams.

Benefits

Health benefits

Discretionary bonus plan

Stock option grants

401(k) with match

Paid time off

Qualifications

• Minimum 5 years of industry experience in drug development.
• Experience in clinical studies and protocols management.
• Demonstrates success in clinical medicine and biomedical research.

Responsibilities

• Contribute to clinical development strategy for HCM and HFpEF.
• Serve as medical expert and plan clinical trials.
• Analyze clinical findings to support safety and efficacy decisions.

Skills

Communication

Cross-functional collaboration

Analytical skills

Education

MD or MD/PhD

Board Certified or Eligible in Internal Medicine

Subspecialty training in Cardiovascular Medicine

Job description

Senior Director, Cardiovascular Clinical Development (EDG-2025008)

Join to apply for the Senior Director, Cardiovascular Clinical Development (EDG-2025008) role at Edgewise Therapeutics

Senior Director, Cardiovascular Clinical Development (EDG-2025008)

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Join to apply for the Senior Director, Cardiovascular Clinical Development (EDG-2025008) role at Edgewise Therapeutics

Senior Director, Cardiovascular Clinical Development

About Edgewise Therapeutics:

At Edgewise, we are on a mission to discover new medicines that improve the lives of patients facing serious muscle disease. Our intimate knowledge of muscle biology and biophysics along with our ability to identify and design muscle specific precision small molecules have enabled us to rapidly advance our skeletal muscle and cardiac muscle product candidates into the clinic while also building a robust pre-clinical pipeline. With this focus on therapeutics designed to protect and improve muscle health, our goal is to dramatically enhance the lives of people living with progressive muscle disorders.

We have assembled an experienced and highly motivated leadership team with a strong track record in the biotechnology and pharmaceutical industry to build the leading, global muscle disease biopharmaceutical company. Come join us make a significant difference in the lives of patients!

About the Position:

The Senior Director of Cardiovascular Clinical Development will be a key member of the clinical team working to develop our clinical assets. This individual will be viewed as a strategic partner to the VP of Clinical Development and other members of the CV clinical development team, contributing to the strategy and standards of operational excellence and implementation across clinical development.

Essential Job Duties and Functions:

• Contribute to hypertrophic cardiomyopathy (HCM) and heart failure with preserved ejection fraction (HFpEF) clinical development strategy with an eye towards operational excellence in execution and innovation.
• Serve as medical expert on early and late cardiovascular development programs and help plan clinical trials . Test the clinical hypotheses and early proof of concept of assets.
• Act as a sponsor medical monitor to help ensure participant safety.
• Analyze and summarize the clinical findings from studies to support decisions regarding safety and efficacy as well as new drug applications, clinical study reports, and publications.
• Participate in internal and joint internal/external research project teams relevant to the development of new compounds. Aid in the selection of Scientific Advisory Committees for compounds in development and manage/participate in advisory board discussion.
• Contribute to clinical sections of regulatory documents (INDs, briefing documents for scientific advice, BLA);
• Develop strategies for complex issues with potential for significant regulatory compliance impact. Ensure continued regulatory compliance of products.
• Collaborate with the Business Development function to help refine strategy and evaluate opportunities as they arise.
• Identify scientifically and operationally strong investigators who can assist in the development of our company’s investigational compounds.
• Develop and maintain relationships with prominent clinical investigators in his/her particular field of interest.
• Represent the Company in various external forums as needed, increasing the profile of the Company through outstanding communication skills.
• Read, understand, and comply with all workplace health and safety policies, safe work practices, and company policies and procedures.
• Perform other duties as assigned by supervisor.
  
  
  

Required Education, Experience and Skills:

• MD or MD/PhD. Board Certified or Eligible in Internal Medicine. Subspecialty training in Cardiovascular Medicine and/or genetic cardiomyopathies preferred.
• Must have experience in industry or as senior faculty in academia
• Minimum 5 years of industry experience in drug development or biomedical research experience in academia
• Demonstrated success in overseeing clinical studies and protocols
• Proven track record in clinical medicine and background in biomedical research.
• Ability to develop strong cross-functional working relationships with a diverse team of colleagues.
• Closely connects with key stakeholders globally (regulators, KOLs, universities, VCs, biotechnology companies, clinical community, patient groups, policymakers).
• Builds a high level of trust and partnership with the Executive Leadership Team.
• Has outstanding verbal and written communication and presentation skills
• Able to travel on company business about twenty (20) percent of the time to manage future or ongoing clinical research projects.
  
  
  

Performance and personal competencies required:

Setting Strategy

• The inclination to seek and analyze data from a variety of sources to support decisions and to align others with the organization's overall strategy.
• An entrepreneurial and creative approach to developing new, innovative ideas that will stretch the organization and push the boundaries within the industry.
  
  
  

Executing for Results

• The ability to set clear and challenging goals.
• Comfortable with ambiguity and uncertainty; the ability to adapt nimbly and lead others through complex situations.
• Viewed by others as having a high degree of integrity and forethought in his/her approach to making decisions; the ability to act in a transparent and consistent manner while always taking into account what is best for the organization.
  
  
  

Relationships and Influence

• Naturally connects and builds strong relationships with others, demonstrating strong emotional intelligence and an ability to communicate clearly and persuasively.
• An ability to inspire trust and followership in others through compelling influence, powerful charisma, passion in his/her beliefs, and active drive.
• Encourages others to share the spotlight and visibly celebrates and supports the success of the team.
  
  
  

Our Benefits: We are proud to offer health benefits, a discretionary bonus plan, stock option grants. a stock purchase plan, a 401(k) with match and paid time off to our team members as part of their compensation plan.

There is no deadline because the employer accepts applications on an ongoing basis.

Edgewise does not accept resumes from recruitment agencies for this position. Please do not send resumes to Edgewise employees or the company location. Edgewise is not responsible for any fees related to unsolicited resumes.

Seniority level

• Seniority level

  Director

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

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