Senior Director, Bioinformatics

Scorpion Therapeutics; Palo Alto (CA); Hybrid; USD 180,000 - 240,000; Full time

Job summary

Scorpion Therapeutics in Palo Alto seeks a Senior Director of Bioinformatics to lead strategic and operational efforts in multiomics data analysis to support its oncology pipeline. You will oversee biomarker discovery, patient stratification, and companion diagnostic development, and you will drive AI/ML applications for predictive modeling across discovery to clinical stages.

The role requires a PhD and 15+ years in biotech with oncology experience, along with cloud expertise and a record of

Qualifications

• PhD in Bioinformatics, Computational Biology, Genetics, or related field.
• 15+ years in biotech/pharma, with oncology experience preferred.
• expertise in NGS pipelines, multiomics integration, statistical genomics, single-cell/spatial analysis, ML, and cloud platforms (AWS, Azure, GCP).
• proficient in R, Python, data visualization.
• supported biomarker strategies and regulatory submissions.

Responsibilities

• oversee biomarker discovery, patient stratification, mechanism of response, resistance, and companion diagnostic development;
• develop and execute computational strategies across discovery, translational, and clinical stages;
• lead integration of complex datasets (WES, WGS, RNA-seq, single-cell, spatial transcriptomics, proteomics, ctDNA, digital pathology);
• drive AI/ML applications for predictive modeling;
• establish best practices for data governance and infrastructure;
• collaborate with multidisciplinary teams and external partners;
• support regulatory submissions and operational excellence.

Skills

Bioinformatics

Multiomics integration

NGS pipelines

Single-cell analysis

AI/ML applications

R

Python

Data visualization

Cloud platforms

Education

PhD in Bioinformatics, Computational Biology, Genetics, or related field

Tools

AWS

Azure

GCP

Job description

Role

Senior Director of Bioinformatics leading strategic and operational efforts in genomic, proteomic, and other multiomics data analysis to support Summit’s oncology pipeline.

Responsibilities

• oversee biomarker discovery, patient stratification, mechanism of response, resistance, and companion diagnostic development;
• develop and execute computational strategies across discovery, translational, and clinical stages;
• lead integration of complex datasets (WES, WGS, RNA-seq, single-cell, spatial transcriptomics, proteomics, ctDNA, digital pathology);
• drive AI/ML applications for predictive modeling;
• establish best practices for data governance and infrastructure;
• collaborate with multidisciplinary teams and external partners;
• support regulatory submissions and operational excellence.

Qualifications

• PhD in Bioinformatics, Computational Biology, Genetics, or related field;
• 15+ years in biotech/pharma, with oncology experience preferred;
• expertise in NGS pipelines, multiomics integration, statistical genomics, single-cell/spatial analysis, ML, and cloud platforms (AWS, Azure, GCP);
• proficient in R, Python, data visualization;
• supported biomarker strategies and regulatory submissions.

Preferred

oncology drug development, companion diagnostics, AI-powered pathology, publications, and cross-functional team experience.

High-Value

Oncology, biomarker discovery, precision medicine, multiomics, AI/ML, regulatory support, clinical and translational research.

Work setup

not specified, likely hybrid or remote based on industry norms.