Senior Director, AIRx DMPK & Modeling Lead

Scorpion Therapeutics; Boston (MA); On-site; USD 300,000 - 420,000; Full time

Job summary

You will oversee CRO activities, embed DMPK insights into AI-driven decision cycles, and connect preclinical data to clinical hypotheses, contributing to IND-enabling packages through cross-functional collaboration in a fast-paced environment.

Qualifications

• PhD required with 12-15+ years industry experience in pharmaceutical DMPK and modeling.
• Proven contribution to IND filings.
• Experience managing external CROs and integrating AI/ML data into decision-making.

Responsibilities

• Define and execute quantitative and mechanistic modeling strategies.
• Oversee CRO activities to generate high-quality data.
• Embed DMPK insights into AI-powered decision-making cycles.
• Link preclinical data to clinical hypotheses.

Skills

AI/ML data integration

CRO management

Cross-functional collaboration

Education

PhD in relevant field

Tools

AI platforms

Job description

Role:

DMPK & Modeling Lead within Takeda's AI-driven Discovery Automation & Robotics (DAR) unit, focusing on integrating DMPK, PK/PD, PBPK/QSP, and AI-enabled modeling to inform early drug discovery and clinical strategies for large molecules, including biologics.

Responsibilities:

• define and execute quantitative and mechanistic modeling strategies, oversee CRO activities to generate high-quality data, embed DMPK insights into AI-powered decision-making cycles, and link preclinical data to clinical hypotheses.

Requirements:

• PhD in a relevant scientific discipline with 12-15+ years industry experience in pharmaceutical DMPK and modeling, proven contribution to IND filings, externalized CRO management expertise, and AI/ML data integration experience.

Preferred:

• therapeutic area experience represented in Takeda's portfolio.

HighValue:

• leadership in early discovery, biologics and small molecules, AI-enabled modeling, cross-functional collaboration, external CRO oversight, and contribution to IND-enabling packages.

Location:

Boston, MA; full-time, exempt.