Senior Director, AI Enablement & Governance

OneOncology, LLC; Nashville (TN); On-site; USD 180,000 - 250,000; Full time

Job summary

OneOncology, LLC seeks a Senior Director, AI Enablement & Operations to lead enterprise AI governance, validation, and production oversight. You will establish risk-based frameworks to ensure safe deployment of AI, maintain audit-ready documentation, and scale the function across the portfolio.

You will manage a small team, partner with Technology, Security, Compliance, Clinical, and business leaders to enable responsible AI adoption while protecting PHI and patient care.

Qualifications

• 10+ years of progressive technology leadership with AI/ML delivery and validation.
• Healthcare experience with HIPAA and PHI handling obligations.
• Proven governance, validation, or QA programs for production systems.
• SOX ITGC knowledge and audit support.
• Strong leadership and cross-functional team development.

Responsibilities

• Own and operationalize the enterprise AI validation framework, risk-tiered by patient-safety impact and PHI exposure.
• Require pre-production accuracy testing against defined performance thresholds before any high-risk AI system enters production use.
• Stand up continuous production monitoring - model drift, error rates, throughput and backlog, and change detection - with defined alerting thresholds and escalation paths.
• Define and enforce human-in-the-loop boundaries for agentic workflows, including PHI transmission to external parties.
• Maintain rollback provisions for every high-risk AI system and ensure they are tested and executable.
• Retain validation and monitoring evidence in SIEM/Azure, ServiceNow, SharePoint, OneAnalytics/Databricks for SOX ITGC readiness.
• Lead end-to-end validation of prior authorization agent and its PHI handling in payor portals.
• Establish accountability for agent oversight: audit trails, explainability, drift detection, error monitoring, benchmarking.
• Operate a single enterprise intake for AI pilot requests with kill criteria at intake.
• Run vendor evaluations or RFPs by product category with a single selection process per category.
• Conduct vendor diligence on security posture, PHI handling, data rights, integration burden, and independent testing.
• Own production operations for AI systems: incident response, change control, and coordination with security and platform teams.
• Enable rapid, safe adoption of low-risk productivity AI with usage guidance.
• Hub-and-spoke model with enterprise functions and shared delivery.
• Report AI portfolio status and risk to executives on cadence.
• Own Claude Enterprise platform end to end: admin, security, usage policy, adoption roadmap.
• Drive adoption by embedding with business teams to build agents and workflows in real work.
• Own enterprise connector strategy: Claude integration with Salesforce, Monday.com, ServiceNow, Databricks, GitHub, M365, Workday.

Skills

AI governance

Model validation

MLOps

Healthcare / HIPAA

SOX ITGC

Leadership & team building

Risk management

Audit readiness

Cross-functional collaboration

Tools

Azure

Databricks

ServiceNow

HL7/FHIR

Job description

OneOncology, LLC seeks a Senior Director, AI Enablement & Operations to lead enterprise AI governance, validation, and production oversight. You will establish risk-based frameworks to ensure safe deployment of AI, maintain audit-ready documentation, and scale the function across the portfolio.

You will manage a small team, partner with Technology, Security, Compliance, Clinical, and business leaders to enable responsible AI adoption while protecting PHI and patient care.