Senior Data Scientist

Institute For Medical Research, Inc.; Durham (NC); On-site; USD 74,000 - 91,000; Full time

Job summary

The Institute For Medical Research, Inc. seeks a Senior Data Scientist to support clinical informatics and biostatistics within the Durham VA Cardiology program, translating complex questions into reliable data, analyses, and actionable reporting.

You'll build scalable data pipelines, run advanced analytics, and create dashboards using REDCap, Power BI, and other tools, collaborating with investigators and operational partners across the analytic lifecycle from planning to dissemination.

Qualifications

• Advanced training or equivalent professional experience in data science or related field.
• Experience analyzing complex clinical data and collaborating with clinical or research teams.
• Proficiency in SQL and one or more analytics languages with reproducible workflows.
• Experience with statistical analysis and interpretation of observational or clinical-study data.
• Ability to work independently, manage multiple projects, and communicate with diverse audiences.

Responsibilities

• Define cohorts, outcomes, exposures, data requirements for observational studies, trials, and quality-improvement initiatives.
• Extract, integrate, transform, and curate structured clinical data from VA CDW and other sources (lab, meds, procedures, diagnoses, encounters, vitals).
• Develop reusable data pipelines, analytic datasets, data dictionaries, validation checks, and traceability procedures.
• Perform systematic data quality assessment and reconcile with source systems.
• Provide statistical programming and analytic support using descriptive, inferential, regression, longitudinal, and survival methods.
• Contribute to study design, analytic plans, variable definitions, and interpretation of results.
• Create validated tables, listings, figures, and reports for investigators and leadership.
• Support protocols, abstracts, manuscripts, and grant applications with analytic documentation.
• Design and maintain data-capture, workflow, and reporting solutions using REDCap, Power BI, SharePoint, Power Automate.
• Automate processes for patient identification, eligibility screening, scheduling, reminders, and missing-data reviews.
• Develop dashboards tracking enrollment, data completeness, and study milestones.
• Test, document, refine, and sustain reporting tools while reducing manual processing.
• Evaluate advanced methods and ML approaches for clinical questions.
• Support research involving ECG, echocardiographic, and clinical data; develop prediction models.
• Develop reproducible ML pipelines and validation.
• Promote reproducible research via version control and standardized programming practices.
• Provide mentorship to analysts and staff.

Skills

SQL

R

Python

SAS

Data visualization

Biostatistics

Clinical informatics

Workflow automation

Education

Advanced degree in data science or related field

Tools

REDCap

Power BI

SharePoint

Power Automate

VA CDW/VINCI

Job description

Position Description: Senior Data Scientist

Salary: $82,500 annually

Position Summary

The Senior Data Scientist will support clinical research and quality-improvement initiatives within the Durham VA Cardiology through clinical informatics, biostatistics, data engineering, workflow automation, and research reporting. The incumbent will work closely with cardiologists, investigators, pharmacists, research coordinators, biostatisticians, informaticians, and operational partners to translate clinical and research questions into reliable data, rigorous analyses, and practical reporting tools.

The position will span the full analytic lifecycle, from study planning and data-source identification through extraction, processing, quality control, statistical analysis, visualization, interpretation, and dissemination. The incumbent will also help design sustainable data workflows and research infrastructure that can be adapted across current and future Cardiology studies.

Key Responsibilities

Clinical Informatics and Data Management

• Partner with clinical investigators to define cohorts, outcomes, exposures, time windows, and data requirements for observational studies, clinical trials, implementation projects, and quality-improvement initiatives.
• Extract, integrate, transform, and curate structured clinical data from the VA Corporate Data Warehouse and other approved sources, including laboratory, medication, procedure, diagnosis, encounter, vital-sign, and longitudinal follow-up data.
• Develop reusable and well-documented data pipelines, analytic datasets, data dictionaries, validation checks, and source-to-output traceability procedures.
• Perform systematic data quality assessment, including completeness, consistency, duplicate identification, temporal validation, and reconciliation with clinical or operational source systems.

Biostatistics and Research Analytics

• Provide statistical programming and analytic support using appropriate descriptive, inferential, regression, longitudinal, survival, and other methods based on the study design and research question.
• Contribute to study design, feasibility assessment, analytic plans, variable definitions, sample-size considerations, interpretation of results, and sensitivity or subgroup analyses in collaboration with investigators and biostatisticians.
• Create validated tables, listings, figures, visualizations, and summary reports for investigators, sponsors, clinical teams, and leadership.
• Support preparation of protocols, abstracts, manuscripts, presentations, grant applications, and other scientific deliverables, including analytic documentation and methods sections.

Workflow Automation and Reporting Systems

• Design and maintain research data-capture, workflow, and reporting solutions using platforms such as REDCap, Power BI, SharePoint, Power Automate, and other approved tools.
• Automate processes such as patient identification, eligibility screening, task generation, follow-up scheduling, reminders, notifications, missing-data review, and escalation of overdue activities.
• Develop operational and research dashboards that track enrollment, follow-up, data completeness, clinical measures, study milestones, and other agreed performance indicators.
• Work with end users to test, document, refine, and sustain reporting tools and automated workflows while reducing unnecessary manual processing.

Advanced Analytics and Methodological Development

• Evaluate and apply advanced statistical, predictive, or machine-learning methods when appropriate to the clinical question, available data, study maturity, and validation requirements.
• Support emerging Cardiology research involving ECG, echocardiographic, and clinical data, including development and evaluation of prediction models, while emphasizing clinical interpretability, reproducibility, and generalizability.
• Develop and implement reproducible machine-learning pipelines using ECG, echocardiographic, and clinical data, including data preparation, quality control, model development and evaluation, validation, and reporting.
• Assess new analytic methods and data sources and recommend practical approaches that complement established clinical informatics and biostatistical workflows.

Collaboration, Governance, and Reproducibility

• Serve as a data-science and informatics resource for Cardiology investigators and multidisciplinary research teams, communicating technical findings clearly to clinical and nontechnical audiences.
• Apply applicable VA privacy, information-security, regulatory, and research-governance requirements to data access, processing, analysis, reporting, and dissemination.
• Promote reproducible research through version control, standardized programming practices, transparent documentation, validation, and clear description of analytic assumptions and limitations.
• Provide technical guidance or mentorship to analysts, trainees, investigators, and project staff as needed.

Required Qualifications

• Advanced training or equivalent professional experience in data science, biostatistics, biomedical or clinical informatics, epidemiology, engineering, computational biology, or a related quantitative field.
• Substantial experience analyzing complex clinical, biomedical, or health-services data and collaborating with clinical or research teams.
• Advanced proficiency in SQL and one or more analytic languages such as R, Python, or SAS, with demonstrated ability to develop validated and reproducible workflows.
• Experience with statistical analysis, data visualization, research reporting, and interpretation of observational or clinical-study data.
• Ability to work independently, manage multiple projects, establish analytic priorities, and communicate effectively with scientific, clinical, operational, and leadership audiences.

Preferred Qualifications

• Experience with cardiovascular research, VA data systems, VA Corporate Data Warehouse/VINCI, or comparable large-scale electronic health record repositories.
• Experience developing clinical research databases, dashboards, and workflow automation using REDCap, Power BI, SharePoint, Power Automate, or related platforms.
• Experience with longitudinal analysis, survival analysis, predictive modeling, machine learning, or analysis of ECG and other physiologic data.
• Record of contributions to peer-reviewed publications, grant proposals, clinical research programs, or implemented analytic products.