Senior Data Architecture Lead – Snowflake Platform

Amylyx Pharmaceuticals

Cambridge (MA)

Remote

USD 190,000 - 206,000

Full time

14 days+

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Job summary

Amylyx Pharmaceuticals is seeking an Associate Director, Data Architecture to lead the design, implementation, and evolution of our enterprise data platform as we prepare for commercial growth and future product launches.

This hands-on leadership role centers on Snowflake, data governance, and BI across Commercial, Medical Affairs, Finance, R&D, and Quality, partnering with vendors and internal teams to deliver trusted data, scalable pipelines, and AI-enabled insights.

Qualifications

Bachelor's degree in CS, IS, Eng., or related field.
10+ years of experience in Data Architecture, Data Engineering, DW, or BI.
5+ years leading enterprise-scale data architecture initiatives.
3+ years hands-on Snowflake design/implementation.
Experience supporting commercial operations within pharmaceutical or biotechnology.
Strong experience designing and implementing modern data warehouses, data lakes, and analytical platforms.
Expertise with Snowflake, SQL/SnowSQL, Python, Talend/Qlik Data Integration, Power BI
REST APIs and enterprise integrations
Data modeling, Data governance, MDM, Data quality frameworks, Security and access controls
Experience designing end-to-end solutions from source systems through reporting and analytics.
Experience managing implementation partners, consultants, and MSPs.
Ability to effectively communicate complex technical concepts to executive, business, and technical audiences.
Experience designing data products that support AI, machine learning, or GenAI initiatives.
Experience implementing enterprise data governance or MDM programs.

Responsibilities

Define and maintain Amylyx's enterprise data architecture roadmap and target-state data platform.
Lead data architecture and solution design for new business domains including Commercial, Finance, HR, R&D, Quality, and Regulatory.
Establish scalable data architecture patterns for ingestion, transformation, storage, governance, reporting, and analytics.
Develop and maintain enterprise data models, canonical data structures, and integration standards.
Lead development and expansion of Amylyx's Commercial Data Hub and enterprise data warehouse.
Design and oversee integration of key commercial data sources including CRM, Specialty Pharmacy, Claims, Formulary, and more.
Support commercial launch planning through delivery of high-quality, trusted data and reporting capabilities.
Collaborate with Commercial Operations and Analytics teams to enable KPI reporting, territory management, incentive compensation, customer analytics, and launch performance tracking.
Provide technical leadership for Snowflake-based data solutions.
Design ELT/ETL processes utilizing Snowflake, SQL, Python, Talend/Qlik Data Integration, APIs, and cloud-native technologies.
Define standards for data ingestion, transformation, orchestration, monitoring, and automation.
Review and approve technical designs, code, and implementation deliverables from internal and external teams.
Drive optimization of performance, scalability, security, and maintainability across the platform.
Partner with business and IT leaders to establish data governance processes and standards.
Support enterprise MDM strategy and implementation.
Define standards for data quality, metadata, lineage, reference data, and stewardship.
Ensure compliance with applicable GxP, privacy, security, and regulatory requirements.
Act as the primary technical lead for data architecture initiatives and strategic programs.
Manage relationships with implementation partners, managed service providers, and data vendors.
Establish best practices, development standards, code review processes, and operational procedures.
Mentor technical resources and contribute to building a Data & Analytics Center of Excellence.