Senior Computational Research Scientist

Thecentermemphis; Memphis (TN); On-site; USD 104,000 - 186,160; Full time

Job summary

Thecentermemphis in Memphis, Tennessee is looking for a Senior Computational Research Scientist who will lead and develop computational research projects. This role requires a strong background in computational chemistry, experience with molecular dynamics, and proficiency in scientific programming languages such as R and Python. The ideal candidate will have minimal supervision and be responsible for guiding other researchers and presenting findings. A Bachelor's degree is required, with a Master's or PhD preferred.

Qualifications

• Strong background in computational chemistry is required.
• Experience with molecular dynamics and docking techniques.
• Familiarity with high performance computing resources.
• Proficiency in scientific computing languages, such as R and Python.

Responsibilities

• Lead computational research projects with minimal supervision.
• Develop new computational methods.
• Identify and interpret relevant data.
• Present research findings effectively.

Skills

Computational chemistry

Molecular dynamics simulations

Molecular docking

Programming in R

Programming in Python

High performance computing

Education

Bachelor's degree in related field

Master's degree or PhD preferred

Tools

Knime

RDKit

ChemProp

Job description

The Senior Computational Research Scientist leads, performs, and develops computational research projects under minimal supervision.

The Department of Chemical Biology and Therapeutics (CBT) is seeking a highly motivated computational chemist interested in using state‑of‑the‑art techniques in computer‑aided drug design, virtual screens, and structure‑guided drug design to discover novel small molecule modulators of targets relevant to pediatric disease. The applicant is expected to work alongside domain experts in the biology of pediatric disease, chemists, and pharmacologists, as well as the various institutional shared resources devoted to translational science, in a collaborative project team environment.

The applicant must have a strong background in computational chemistry, including molecular dynamics simulations, molecular docking, pharmacophore modeling, quantitative structure activity relationship modeling, and chemical informatics. The applicant must also be comfortable using high performance computing resources; and developing, maintaining, and mining chemical and biological databases. Proficiency in scientific computing languages, such as R and Python, and open‑source programming tools such as Knime, RDKit, and ChemProp is a plus.

Job Responsibilities

• Lead computationally focused scientific research projects with minimal supervision from their PI. Develop new computational methods.
• Identify, process, organize, interpret, review, and report relevant data.
• Direct data collection.
• Present research to colleagues within and outside the institution; draft a complex manuscript with minimal supervision, as required.
• Regularly train and oversee the work of others in computational research and procedures.
• Perform other duties as assigned to meet the goals and objectives of the department and institution.
• Maintains regular and predictable attendance.

Minimum Education and/or Training

• Bachelor's degree in Bioinformatics, Molecular Biology, Biochemistry, Computer Science, or related field.
• Master's degree or PhD preferred.

Minimum Experience

• Minimum Requirement: Bachelor's degree and 7+ years of relevant experience.
• Experience Exception: Master's degree and 5+ years of relevant experience (OR) PhD with 2+ years of relevant experience.
• Rough criteria for this position based on publication output: 1-2 first author papers IF > 10 (or equivalent contribution to other research outputs).
• Prior experience in computational research techniques and processes.
• Proven performance in earlier role/comparable role.

Compensation

A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Senior Computational Research Scientist.

Explore our exceptional benefits!

Equal Opportunity Employer

St. Jude is an Equal Opportunity Employer.

No Search Firms

St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.