Senior Computational Biologist - Epigenomics & 3D Genome

NYU Langone Health, Skok Lab; New York (NY); On-site; USD 70,000 - 110,000; Full time

Job summary

NYU Langone Health's Skok Lab seeks a computational scientist to join a multidisciplinary program investigating chromatin organization, epigenomics, and gene regulation. The position may be a Postdoctoral Fellow or Senior Computational Biologist / Non-Tenure-Track Assistant Professor, depending on experience.

The role involves developing pipelines for long-read data, integrating multi-omics, collaborating with experimental scientists, and pursuing independent computational directions in a

Qualifications

• PhD in Computational Biology, Bioinformatics, Computer Science, Statistics, Biology, or related quantitative field.
• Strong programming skills in Python, R, and Bash/Linux.
• Experience with bioinformatics, genomics, computational biology, or related quantitative analyses.
• Demonstrated ability to analyze and interpret complex biological datasets.
• Interest or experience in computational epigenomics, chromatin biology, genomics, or machine learning.
• Ability to work independently while collaborating in a multidisciplinary environment.
• Strong written and oral communication skills.

Responsibilities

• Develop and apply computational pipelines for long-read and single-molecule sequencing data.
• Analyze per-molecule DNA methylation, chromatin accessibility, and chromatin-state information.
• Apply statistical and machine-learning approaches to study nucleosome organization and transcription factor binding.
• Integrate multi-omics datasets to investigate chromatin architecture and gene regulation.
• Develop reproducible workflows using Snakemake, Nextflow, or similar platforms.
• Lead or contribute to computational analyses for collaborative projects.
• Collaborate closely with experimental scientists to integrate computational and molecular data.
• Present findings at lab meetings, conferences, and publications.
• Develop independent computational research questions and directions.

Skills

Python

R

Bash/Linux

Statistical analysis

Machine learning

Independent work

Communication skills

Collaborative research

Education

PhD in Computational Biology or related field

Tools

Snakemake

Nextflow

HPC/Cloud

Remora

Megalodon

Tombo

Job description

NYU Langone Health's Skok Lab seeks a computational scientist to join a multidisciplinary program investigating chromatin organization, epigenomics, and gene regulation. The position may be a Postdoctoral Fellow or Senior Computational Biologist / Non-Tenure-Track Assistant Professor, depending on experience.

The role involves developing pipelines for long-read data, integrating multi-omics, collaborating with experimental scientists, and pursuing independent computational directions in a