Senior Clinical Trial Operations Lead — Remote

Immatics; United States; Remote; USD 95,000 - 120,000; Full time

Benefits offered by this job

Health, Dental, Vision Insurance

4 weeks vacation

12 company paid holidays

7 days of sick time

Life insurance 100% employer-paid up

Job summary

Immatics is hiring a Senior Clinical Trial Associate (CTA) to join our Clinical Operations team in a fully remote role based in the United States. You will support start-up through closeout of clinical trials, ensuring documentation quality and compliance across CTMS/eTMF systems.

The position emphasizes collaboration with CROs, vendors, and investigative sites, facilitating audits, and maintaining study records.

Qualifications

• Bachelor’s degree in life sciences, nursing, or a related field.
• 4+ years’ experience in clinical research with ICH-GCP knowledge.
• Experience in pharmaceutical or biotech industry.
• Strong understanding of trial processes and quality standards.

Responsibilities

• Support trial start-up, activation, maintenance, and closeout activities with timely collection of essential study documents.
• Maintain and perform quality reviews of trial information within CTMS, eTMF, and other clinical systems.
• Partner with internal teams, CROs, vendors, and investigative sites to drive study execution and resolve operational issues.
• Support inspection and audit readiness through accurate, complete, and compliant trial documentation.
• Coordinate trial-related meetings, documentation reviews, approvals, and key administrative activities.
• Manage purchase orders, invoices, investigator payments, and study-related financial tracking.
• Prepare, review, and quality-check study documents, reports, trackers, and investigator site files.
• Support TMF and ISF maintenance, reconciliation, and quality oversight to ensure ongoing compliance.
• Coordinate training assignments, system access, and compliance tracking for study teams.
• Monitor site issues, action items, and data query resolution to support study milestones.
• Support tracking and follow-up of outstanding EDC queries and facilitate timely resolution by appropriate study team members and/or sites.
• Facilitate site communications, including study updates, newsletters, and distribution of trial materials.
• Contribute to risk identification, issue escalation, process improvements, and inspection readiness efforts.
• Support the development of SOPs, work instructions, guidance documents, and training materials.
• May assist with remote and on-site monitoring activities, as appropriate.

Skills

Problem-solving

Independent work

Clinical operations understanding

Communication skills

Team collaboration

Education

Bachelor’s degree in life sciences, nursing, or related field

Tools

CTMS

eTMF

Clinical systems

Job description

Immatics is hiring a Senior Clinical Trial Associate (CTA) to join our Clinical Operations team in a fully remote role based in the United States. You will support start-up through closeout of clinical trials, ensuring documentation quality and compliance across CTMS/eTMF systems.

The position emphasizes collaboration with CROs, vendors, and investigative sites, facilitating audits, and maintaining study records.