Senior Clinical Trial Manager — Oncology Operations Lead

Treeline; Watertown (MA); On-site; USD 120,000 - 180,000; Full time

Job summary

Treeline is seeking a Senior Clinical Trial Manager with oncology-focused Clinical Operations experience to join our growing Clinical Development group. This role reports to the VP of Clinical Operations and will be responsible for providing trial management support for oncology programs, including study materials, enrollment tracking, and site and CRO/vendor relationship management.

Key duties include overseeing CRO activities to ensure compliance with ICH/GCP, regulatory rules, and SOPs;

Qualifications

• Bachelor’s degree or equivalent in biomedical or life science field.
• 5–8+ years of trial management experience as primary Clinical Trial Manager (or equivalent).
• Oncology experience required.
• Strong understanding of global regulatory and compliance requirements for clinical research.

Responsibilities

• Clinical Operations point of contact for execution of clinical studies in compliance with ICH/GCP and SOPs.
• Manage clinical CROs and study vendors from initial contact to final study deliverables.
• Lead external CRO trial management team to ensure conduct per regulations and SOPs.
• Coordinate CRO activities including monitoring, data management, medical monitoring, and safety.
• Provide operational input into study documents (protocols, informed consent, CRFs).
• Develop and maintain study deliverables (timelines, plans) with stakeholders.
• Identify and mitigate potential study risks.
• Develop training/materials for study team, sites, and vendors.
• Attend site visits and support TMF management.

Education

Bachelor’s degree, or equivalent, in a biomedical, life science or related field

Job description

Treeline is seeking a Senior Clinical Trial Manager with oncology-focused Clinical Operations experience to join our growing Clinical Development group. This role reports to the VP of Clinical Operations and will be responsible for providing trial management support for oncology programs, including study materials, enrollment tracking, and site and CRO/vendor relationship management.

Key duties include overseeing CRO activities to ensure compliance with ICH/GCP, regulatory rules, and SOPs;