Senior Clinical Trial Manager — Hybrid/Remote Lead

Kailera Therapeutics, Inc.; Waltham (MA); Hybrid; USD 143,000 - 175,000; Full time

Benefits offered by this job

Health coverage

Wellness stipend

Annual bonus opportunities

Equity grants

Job summary

Kailera Therapeutics, Inc. in Waltham, MA is seeking a Senior Clinical Trial Manager to lead end-to-end trials across development.

The role requires onsite/hub-based work with remote options, coordinating CROs, vendors, and cross-functional teams to hit milestones on time and within budget. The ideal candidate has 8+ years of trial experience, a Bachelor’s in life sciences, strong GCP/ICH knowledge, and excellent communication skills.

Qualifications

• 8+ years of clinical trial experience, including direct management of CROs and vendors.
• Ability to lead cross-functional study teams and drive programs independently.
• Strong knowledge of GCP/ICH and regulatory frameworks.

Responsibilities

• Lead end-to-end trial execution and oversight of CROs and vendors.
• Coordinate cross-functional timelines, risk mitigation, and study objectives.
• Manage protocol development, site selection, monitoring, and data review.
• Review trial documents for quality and regulatory compliance.
• Ensure inspection readiness and maintain Trial Master Files.

Skills

Cross-functional leadership

Regulatory knowledge

Project management

Education

Bachelor’s degree in life sciences

Tools

MS Project

Smartsheet

Microsoft Office

Job description

Kailera Therapeutics, Inc. in Waltham, MA is seeking a Senior Clinical Trial Manager to lead end-to-end trials across development.

The role requires onsite/hub-based work with remote options, coordinating CROs, vendors, and cross-functional teams to hit milestones on time and within budget. The ideal candidate has 8+ years of trial experience, a Bachelor’s in life sciences, strong GCP/ICH knowledge, and excellent communication skills.