Senior Clinical Trial Manager

Mosaic People Solutions; California (MO); On-site; USD 120,000 - 170,000; Full time

Benefits offered by this job

Onsite role in San Diego

Job summary

Mosaic People Solutions is seeking a Clinical Trial Manager / Senior Clinical Trial Manager to join its U.S. clinical operations team in San Diego.

This hands-on sponsor-side role oversees studies from planning through close-out, partners with investigators, sites, CROs, and vendors, and ensures compliance with GCP, ICH, and FDA.

The successful candidate will manage timelines, budgets, documentation, and study communications in a fast-paced environment.

Qualifications

• Bachelor’s degree or advanced degree in life sciences, nursing, or a related field.
• 5+ years of clinical trial management or clinical operations experience.
• Sponsor-side clinical trial experience strongly preferred.
• Hands-on experience managing CROs and external vendors.
• Experience managing study timelines, budgets, and documentation.
• Experience working directly with clinical sites and investigators.
• Strong knowledge of GCP, ICH, and FDA clinical research requirements.
• Strong organizational, communication, and project-management skills.
• Ability to work independently in a fast-moving environment.

Responsibilities

• Plan, execute, and manage clinical studies from start-up through enrollment, conduct, and close-out.
• Manage study timelines, milestones, budgets, enrollment, documentation, and operational trackers.
• Select, onboard, and oversee CROs and external vendors.
• Manage CRO scope, performance, budgets, contracts, and deliverables.
• Serve as the primary operational contact for external partners.
• Identify, qualify, and manage clinical sites and investigators.
• Build relationships with investigators and key opinion leaders.
• Support investigator meetings, site training, and study communications.
• Ensure studies comply with GCP, ICH, FDA and applicable requirements.
• Support IRB/Ethics submissions and maintenance of essential study documentation.
• Partner cross-functionally with scientific, regulatory, data, and clinical stakeholders.
• Communicate study status, risks, timelines, and key decisions to leadership.

Skills

Clinical trial management

Sponsor-side experience

CRO/vendor management

GCP/ICH/FDA knowledge

Investigator/site liaison

Education

Bachelor's degree in life sciences

Advanced degree (preferred)

Job description

A growing biotechnology company is seeking a Clinical Trial Manager / Senior Clinical Trial Managerto join its U.S. clinical operations team in San Diego.

This is a hands-on, sponsor-side role with ownership of upcoming clinical studies from planning through close-out. The ideal candidate will be comfortable managing CROs and vendors, partnering directly with investigators and clinical sites, and operating in a fast-paced environment where the clinical function is continuing to grow.

Key Responsibilities

• Plan, execute, and manage clinical studies from start-up through enrollment, conduct, and close-out
• Manage study timelines, milestones, budgets, enrollment, documentation, and operational trackers
• Select, onboard, and oversee CROs and external vendors
• Manage CRO scope, performance, budgets, contracts, and deliverables
• Serve as the primary operational point of contact for external partners
• Identify, qualify, and manage clinical sites and investigators
• Build strong working relationships with investigators and key opinion leaders
• Support investigator meetings, site training, and study communications
• Ensure studies are conducted in compliance with GCP, ICH, FDA, and other applicable requirements
• Support IRB/Ethics Committee submissions and maintenance of essential study documentation
• Partner cross-functionally with scientific, regulatory, data, and clinical stakeholders
• Communicate study status, risks, timelines, and key decisions to leadership

Qualifications

• Bachelor’s degree or advanced degree in life sciences, nursing, or a related field
• 5+ years of clinical trial management or clinical operations experience
• Sponsor-side clinical trial experience strongly preferred
• Hands-on experience managing CROs and external vendors
• Experience managing clinical study timelines, budgets, and documentation
• Experience working directly with clinical sites and investigators
• Strong knowledge of GCP, ICH, and FDA clinical research requirements
• Strong organizational, communication, and project-management skills
• Ability to work independently and operate effectively in a fast-moving environment

Preferred Experience

• Oncology experience strongly preferred
• Diagnostics, liquid biopsy, or early cancer detection experience
• IVD or laboratory-developed test clinical validation experience
• Experience helping build or scale clinical operations within a growing organization

Additional Information

This is an onsite role based in San Diego, California, with some travel to clinical sites and external partner locations expected.

Title and level may be adjusted based on experience.