Senior Clinical Trial Management Associate

Lyell Immunopharma; South San Francisco, Seattle (CA, WA); On-site; USD 128,000 - 160,000; Full time

Job summary

Lyell Immunopharma is seeking a Senior Clinical Trial Management Associate to oversee trial management for next-generation CAR T-cell therapies. The successful candidate will manage vendor relationships, ensure trial deliverables, and mentor junior staff, contributing to groundbreaking cancer treatment advancements. Competitive salary and extensive benefits offered.

Benefits

Subsidized medical, dental, and vision plans

401(k) with company match

Paid time-off benefits, including vacation and sick leave

Employee Equity Incentive Plan

Qualifications

• Minimum 5 years of experience in oncology clinical trial programs.
• Proven clinical studies support for 3+ years; experience in early phase preferred.
• Understanding of FDA regulations and ICH GCP guidelines.

Responsibilities

• Oversees trial-related tasks and vendor management for clinical trials.
• Tracks study expenses and collaborates with the Clinical Operations team.
• Acts as a mentor for junior clinical team members.

Skills

Leadership

Collaboration

Problem Solving

CRO Management

Education

BA/BSc in Life Science or related discipline

Job description

Senior Clinical Trial Management Associate

Seattle, Washington, United States; South San Francisco, California, United States

Using living cells to treat – and sometimes even cure – cancer is one of the most dramatic advances in modern medicine. Patients with hematologic malignancies have been successfully treated with cell therapies. However, these profound results have not yet been achieved in patients with solid tumors, representing approximately 90% of all cancers. And for patients with hematologic malignancies, there is a need for next-generation cell therapies that can deliver increased response rates and longer duration of response. We are a clinical-stage company advancing a pipeline of next-generation CAR T-cell therapies for patients with solid tumors or hematologic malignancies. Lyell’s product candidates are enhanced with novel technology designed to generate T cells that resist exhaustion and have qualities of durable stemness in order to drive durable tumor cytotoxicity and achieve consistent and long-lasting clinical response. We were founded by cell therapy pioneers whose decades of research elevated the broader understanding of T-cell biology and its interaction with cancer. In our quest to advance next-generation CAR T-cell therapies, we have built a fully integrated company capable of discovering new technologies, translating science into therapies, manufacturing cell therapy products, and clinically evaluating them in patients. Our culture is based on Science, Respect, Collaboration, and Courage and reflects who we are, the environment we create, and our mission's urgency.

POSITION SUMMARY:

The individual in this role will be responsible for executing defined tasks in a trial with guidance from the Director/Associate Director/Sr CTM.

KEY ROLES AND RESPONSIBILITIES:

• Completes trial related tasks with a high degree of autonomy; able to step into leadership scope including running Study Management Team meetings and managing vendor partnerships (including central imaging and laboratory vendors that support cell therapy pivotal clinical trials)
• Develops tactical plans, detailed process steps and creates materials in addition to recommending strategic inputs and recommending ways to proactively address problems with solutions.
• Responsible for oversight of trial related tasks; including CRO/vendor management for the defined trial and more complex trial program activities, ensuring deliverables are conducted on a timely, quality basis. Identifies issues and makes recommendations to mitigate issues in a timely manner
• Tracks inputs and deliverables day-to-day in partnership with the Clinical Operations team; identifies ways to improve the way we track study progress, reaches out to cross-functional partners for follow up and pull through.
• Collaborates effectively; operates as a mentor and subject matter expert for more junior clinical team members
• Supports TMF maintenance activities through timely filing of study and vendor documents, assisting with TMF review, reporting findings to CTM
• Continues to learn and apply ICH GCP guidelines; stays current with evolving expectations and applies new protocols as required; recommends processes and procedures that support effective trial management
• Tracks study expenses, as directed by Associate Director or Sr CTM, tracks vendor invoices for vendors being managed. Monitors and adheres to budget targets for assigned vendors

PREFERRED EDUCATION & EXPERIENCE:

• BA/BSc in Life Science or related discipline
• Minimum 5 years experience in Oncology clinical trial programs required
• Proven support of clinical studies for 3+ years; early phase and start-ups a plus
• Track record of collaborating and managing CROs and other external vendors to deliver successful trial outcomes
• Operates effectively in cross-functional, multi-disciplinary teams
• Has understanding of FDA regulations and ICH GCP guidelines; learns how to successfully apply these to studies to drive effective, efficient and timely strategies

Lyell offers its employees a range of compensation and benefits. To assist you with your decision to apply for this role, the following decision to apply for this role, the following information and links to our site highlight our competitive market position and support to our employees and their dependents.

The salary range for this position is $128,000 to $160,000, annually, with the opportunity to earn an annual bonus. The salary range is an estimate, and the actual salary may vary based on Lyell’s compensation practices and an applicant’s qualifications and experience. Employees are also eligible to participate in Lyell’s Equity Incentive Plan.

Our Employee Benefits program is extensive and includes subsidized medical, dental and vision plans from your first day of employment, FSA, Company provided Life and AD&D Insurance as well as STD and LTD Insurance, ESPP, a 401(k) Plan with Company match, mass transit commuter benefits, cell phone reimbursement and a range of supplemental benefits that you may choose to elect. Our paid time-off benefits currently include 18 days’ vacation, 9 day’s sick leave, 8 observed holidays as well as a floating holiday. We also have a summer and a winter office shutdown.

At Lyell, we believe that highest performing teams include people from a wide variety of backgrounds and experiences who respectfully challenge each other. We are committed to building an open, diverse and inclusive culture for all employees. Lyell is proud to be an equal opportunity employer and does not discriminate on the basis of race, color, citizenship status, national origin, ancestry, sex, sexual orientation, age, religion, creed, physical or mental disability, medical condition, marital status, veteran status or any other characteristics protected under applicable federal, state and local laws.

We’ve learned from experience that some of the best people don’t always match our requirements perfectly - if you’re interested and think you could fit, please don’t hesitate to apply.

Apply for this job

*

indicates a required field

First Name *

Last Name *

Email *

Phone *

Location (City) *

Resume/CV *

Enter manually

Accepted file types: pdf, doc, docx, txt, rtf

Enter manually

Accepted file types: pdf, doc, docx, txt, rtf

LinkedIn Profile

Are you legally authorized to work in the U.S.? * Select...

If yes, will you require sponsorship for employment status (e.g. H1B Visa status) now or in the future? * Select...

Are you willing to relocate? * Select...

Have you ever been convicted of a misdemeanor or felony? * Select...

If selected for employment are you willing to submit to a background check? * Select...

How did you hear about Lyell? * Select...

I acknowledge that Lyell participates in E-Verify Select...

If you are hired, you will be required to come onsite to your assigned Lyell office on a regular basis.Our locations are as follows:201 Haskins Way, South San Francisco, CA 94080;500 Fairview Ave N, Seattle, WA 98109;2525 223rd St SE, Bothell, WA 98021 * Select...

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Lyell Immunopharma’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Select...

Voluntary Self-Identification of Disability

Form CC-305

Page 1 of 1

OMB Control Number 1250-0005

Expires 04/30/2026

Voluntary Self-Identification of Disability

Form CC-305 Page 1 of 1 OMB Control Number 1250-0005 Expires 04/30/2026
Why are you being asked to complete this form?

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp .

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

• Alcohol or other substance use disorder (not currently using drugs illegally)
• Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
• Blind or low vision
• Cancer (past or present)
• Cardiovascular or heart disease
• Celiac disease
• Cerebral palsy
• Deaf or serious difficulty hearing
• Diabetes
• Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
• Epilepsy or other seizure disorder
• Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
• Intellectual or developmental disability
• Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
• Missing limbs or partially missing limbs
• Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
• Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
• Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
• Partial or complete paralysis (any cause)
• Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
• Short stature (dwarfism)
• Traumatic brain injury

Disability Status Select...

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.