Senior Clinical Trial Associate (Sr. CTA) NX-1607

NURIX; San Francisco (CA); On-site; USD 135,000 - 147,000; Full time

Job summary

Nurix Therapeutics in Brisbane, CA is seeking a Senior Clinical Trial Associate (Sr. CTA) to own TMF processes end-to-end and mentor junior CTAs. You’ll collaborate with CROs to resolve issues before they escalate and manage study documents with minimal oversight.

The role emphasizes data integrity, vendor coordination, and quality reviews of TMF, with opportunities to shape training materials and SOPs across the CTA team.

Qualifications

• Bachelor’s degree in a science-related field.
• 3–5+ years of Clinical Operations or clinical research experience.
• Ownership of a TMF or vendor relationship from start to finish.
• Ability to resolve CRO/vendor issues independently.
• Experience mentoring junior team members.
• Excellent verbal and written communication skills.
• Proficiency with MS Word, Excel, Outlook, and PowerPoint.

Responsibilities

• Own the study TMF plan end-to-end: development, tracking, and archiving Essential Documents.
• Lead quality reviews of the TMF and resolve discrepancies with the CRO.
• Draft and finalize study documents — plans, manuals, CRFs, and patient materials.
• Serve as a go-to resource for junior CTAs, mentoring and guidance.
• Independently manage clinical supply and lab sample coordination.
• Own data reconciliation issues across systems, involving Data Management as needed.
• Represent Clinical Operations at team meetings and Investigator Meetings.
• Help shape training materials and SOPs used across the CTA team.

Skills

TMF ownership

Vendor management

Mentoring

Communication

MS Office suite

Education

Bachelor’s degree in science

Job description

Senior Clinical Trial Associate (Sr. CTA) NX-1607

Brisbane, California

Senior Clinical Trial Associate (Sr. CTA) NX-1607

You’ve done this before — now do it with more ownership. You’ll run the TMF for your studies end-to-end, work directly with CROs to resolve problems before they become problems, and help the CTAs around you get better at the job.

Position Description

You’ll independently own key operational pieces of our trials — from TMF integrity to vendor coordination — and mentor junior team members along the way.

The Opportunity

• Own the study TMF plan end-to-end: development, tracking, and archiving of Essential Documents across the trial lifecycle
• Lead quality reviews of the TMF and resolve discrepancies directly with the CRO
• Draft and finalize study documents — plans, manuals, CRFs, and patient materials — with minimal oversight
• Serve as a go-to resource for junior CTAs, providing informal mentorship and process guidance
• Independently manage clinical supply and lab sample coordination, flagging risks before they escalated
• Own data reconciliation issues across systems, looping in Data Management only when needed
• Represent Clinical Operations at portions of team meetings and Investigator Meetings
• Help shape training materials and SOPs used across the broader CTA team

What You’ll Bring

• Bachelor’s degree (BS/BA) or equivalent combination of education and work experience in a science-related field
• 3–5+ years of Clinical Operations or clinical research-related experience
• Demonstrated ownership of a TMF or vendor relationship from start to finish
• Comfortable resolving routine CRO/vendor issues independently before escalating
• Experience mentoring or informally guiding junior team members
• Excellent verbal and written communication skills
• Proficiency with MS Word, Excel, Outlook, and PowerPoint

Salary Range: $134,500 - $146,600 annually

The posted range applies to roles based in the San Francisco Bay Area and reflects local market conditions. Where an offer lands within that range depends on the candidate’s relevant experience, technical expertise, and how their background aligns with the role’s requirements.

Location: Onsite -Brisbane, CA

Fit with Nurix Culture and Values

• Strong team orientation; highly collaborative
• Solutions and results-oriented focus
• Hands-on approach; resourceful and open to diverse points of view

About Nurix Therapeutics

Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.