Senior Clinical Trial Associate (Sr. CTA) NX-1607

Nurix Therapeutics; Brisbane (CA); On-site; USD 135,000 - 147,000; Full time

Job summary

Nurix Therapeutics is seeking a Senior Clinical Trial Associate (Sr. CTA) to own TMF integrity and drive study operations end-to-end.

You will work directly with CROs to resolve issues before they arise, draft key study documents, and mentor junior CTAs to strengthen the team’s capabilities. You’ll independently coordinate clinical supply, lab sample management, and data reconciliation across systems, elevating trial quality.

Qualifications

• Bachelor's degree (BS/BA) or equivalent in a science-related field.
• 3–5+ years of Clinical Operations or clinical research experience.
• Demonstrated ownership of a TMF or vendor relationship from start to finish.
• Comfortable resolving routine CRO/vendor issues independently before escalation.
• Experience mentoring or guiding junior team members.
• Excellent verbal and written communication skills.
• Proficiency with MS Word, Excel, Outlook, and PowerPoint.

Responsibilities

• Own the TMF plan end-to-end including development, tracking, and archiving essential documents across the trial lifecycle.
• Lead quality reviews of the TMF and resolve discrepancies with the CRO.
• Draft and finalize study documents—plans, manuals, CRFs, patient materials—with minimal oversight.
• Mentor junior CTAs and provide informal guidance and process coaching.
• Independently manage clinical supply and lab sample coordination, flagging risks early.
• Own data reconciliation issues across systems and loop in Data Management when needed.
• Represent Clinical Operations in team meetings and Investigator Meetings.
• Help shape training materials and SOPs for the CTA team.

Skills

TMF ownership

Vendor management

Mentoring

Communication

Education

BS/BA in science-related field

Tools

MS Word

MS Excel

Outlook

PowerPoint

Job description

Senior Clinical Trial Associate (Sr. CTA) NX-1607

You’ve done this before — now do it with more ownership. You’ll run the TMF for your studies end-to-end, work directly with CROs to resolve problems before they become problems, and help the CTAs around you get better at the job.

Position Description

You’ll independently own key operational pieces of our trials — from TMF integrity to vendor coordination — and mentor junior team members along the way.

The Opportunity

• Own the study TMF plan end-to-end: development, tracking, and archiving of Essential Documents across the trial lifecycle
• Lead quality reviews of the TMF and resolve discrepancies directly with the CRO
• Draft and finalize study documents — plans, manuals, CRFs, and patient materials — with minimal oversight
• Serve as a go-to resource for junior CTAs, providing informal mentorship and process guidance
• Independently manage clinical supply and lab sample coordination, flagging risks before they escape
• Own data reconciliation issues across systems, looping in Data Management only when needed
• Represent Clinical Operations at portions of team meetings and Investigator Meetings
• Help shape training materials and SOPs used across the broader CTA team

What You’ll Bring

• Bachelor’s degree (BS/BA) or equivalent combination of education and work experience in a science-related field
• 3–5+ years of Clinical Operations or clinical research-related experience
• Demonstrated ownership of a TMF or vendor relationship from start to finish
• Comfortable resolving routine CRO/vendor issues independently before escalating
• Experience mentoring or informally guiding junior team members
• Excellent verbal and written communication skills
• Proficiency with MS Word, Excel, Outlook, and PowerPoint

Salary Range: $134,500 - $146,600 annually

The posted range applies to roles based in the San Francisco Bay Area and reflects local market conditions. Where an offer lands within that range depends on the candidate’s relevant experience, technical expertise, and how their background aligns with the role’s requirements.

Location: Onsite - Brisbane, CA

Fit with Nurix Culture and Values

• Strong team orientation; highly collaborative
• Solutions and results-oriented focus
• Hands-on approach; resourceful and open to diverse points of view

About Nurix Therapeutics

Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.