Senior Clinical SAS Programmer – Data, Tables & Reports

Total Trials Company; Durham (NC); On-site; USD 90,000 - 125,000; Full time

Job summary

Total Trials Company in Durham, NC seeks a Senior Statistical Programmer to conduct statistical and database programming for clinical projects. You will ensure alignment with trial protocols, ICH GCP, and regulatory requirements (FDA/EMA) and deliver high-quality data outputs.

Responsibilities include creating derived datasets, tables, listings, and figures, developing SAS macros, and supporting Trial Master File documentation.

Qualifications

• Minimum of four (4) years’ experience in statistical/database programming within a clinical research setting.
• Proficiency in SAS; working knowledge of R is advantageous.
• Bachelor’s or higher in science/biotech or related field and strong regulatory awareness.

Responsibilities

• Perform database programming, including derived items, automated edit checks, and customized reports.
• Conduct pre-processing and post-processing of imported and exported data.
• Perform data quality checks and validation.
• Assist with statistical tables, listings, and graph templates and reports.
• Produce derived datasets, tables, listings, and figures aligned with CDISC standards.
• Develop, maintain, and validate SAS macros.
• Provide biometrics programming support to internal stakeholders and clients.
• Support preparation and review of Trial Master File documentation.

Skills

English communication

Attention to detail

Analytical thinking

Organizational skills

Problem solving

Team collaboration

Education

Graduate or post-graduate degree in science/biotech

Equivalent combination of education and experience

Tools

SAS

R (basic)

Job description

Total Trials Company in Durham, NC seeks a Senior Statistical Programmer to conduct statistical and database programming for clinical projects. You will ensure alignment with trial protocols, ICH GCP, and regulatory requirements (FDA/EMA) and deliver high-quality data outputs.

Responsibilities include creating derived datasets, tables, listings, and figures, developing SAS macros, and supporting Trial Master File documentation.