Senior Clinical Research Project Manager

Massachusetts General Hospital; Boston (MA); On-site; USD 79,000 - 129,000; Full time

Job summary

Mass General Brigham in Boston seeks a Senior Clinical Research Program Manager to oversee strategic and operational directions across a diverse portfolio of clinical studies, including IDE trials and registries.

You will lead a team of clinical research professionals, manage timelines, budgets, and data management, and coordinate with CROs and external vendors to ensure compliance with GCP, FDA regulations, and IRB policies.

Qualifications

• Strong leadership and supervisory capabilities for managing a diverse team.
• Experience navigating regulatory and quality systems in clinical research.
• Ability to develop and oversee budgets and project plans.

Responsibilities

• Oversees strategic and operational decision-making across a diverse portfolio of clinical studies.
• Leads a team of clinical research professionals and coordinates with CROs and stakeholders.
• Monitors timelines, budgets, data management, and regulatory compliance (GCP, FDA, IRB).
• Identifies and mitigates risks and drives process improvements.
• Collaborates with principal investigators and sponsors to ensure study success.

Skills

Leadership

Supervisory Experience

Budget Management

Regulatory Compliance

Communication Skills

Project Management

Education

Bachelor's degree in related field

Master's degree in related field (preferred)

Job description

Site: The General Hospital CorporationMass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.Job SummaryManages all recruitment and collection activities for the studies. Functions independently strategizing directly with the PIs. Responsible for the daily execution of principal duties and responsibilities and aspects of project management and administration including operational, budgetary, grant writing, communication, and research subject education components. Also responsible for direct supervision of all research coordinators.Does this position require Patient Care?NoEssential Functions-Develops detailed protocol documents that meet federal institutional standards.-Ensures study design's compatibility with clinical practices.-Provides critical input as to feasibility of study design and available resources.-Ensures document consistency.-Responsible for developing/managing the clinical trial’s operating and capital budgets.QualificationsEducationBachelor's Degree Related Field of Study required or Master's Degree Related Field of Study preferredCan this role accept experience in lieu of a degree?NoLicenses and CredentialsExperienceResearch Related Experience 5-7 years required and Supervisory Experience 3-5 years preferredKnowledge, Skills and Abilities- Ability to effectively supervise and train Staff.- Excellent judgement and ability to interpret information and protocol.- Ability to make independent effective decisions.- Aptitude for technical problem solving.- Excellent organizational abilities to formulate and complete rigorous timetables.Additional Job Details (if applicable)The Senior Clinical Research Program Manager is responsible for strategic and operational decision-making across a diverse portfolio of clinical research studies, including industry-sponsored and investigator-initiated, multi-site IDE trials, retrospective chart review studies, and registries. The ideal candidate will have experience and expertise in running investigator-held, multi-site IDE trials. In this role, you will oversee all aspects of study planning and execution, including timelines, budgets, and data management; lead a team of clinical research professionals, which may include research nurses, clinical research coordinators, data analysts, contract research organizations (CROs), and external vendors, to ensure deliverables are met; and collaborate with internal and external stakeholders to ensure studies are conducted efficiently and in compliance with Good Clinical Practice, FDA regulations, and IRB policies. Success in this role requires strong leadership and organizational skills, excellent communication skills, the ability to problem-solve with good judgment, a comprehensive understanding of clinical research processes, and the ability to proactively identify and mitigate risks and resolve operational challenges while driving process improvements.Remote TypeOnsiteWork Location55 Fruit StreetScheduled Weekly Hours40Employee TypeRegularWork ShiftDay (United States of America)Pay Range$78,936.00 - $128,928.80/AnnualGrade8At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.EEO Statement:1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.Mass General Brigham Competency FrameworkAt Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.