Senior Clinical Research Associate

Ladders; United States; Remote; USD 111,000 - 138,000; Full time

Benefits offered by this job

Total rewards package

Health coverage

Retirement plan

Life insurance

Employee assistance

Career development

Job summary

Ladders is seeking a Senior Clinical Research Associate to support oncology trials from a remote US-based location. The role emphasizes site management, monitoring quality, subject safety, and RBM-driven study performance.

Ideal candidates have 5+ years of independent trial monitoring, with solid tumor and early development experience, and familiarity with Veeva systems. This position offers comprehensive rewards and healthcare coverage.

Qualifications

• Bachelor's degree in a scientific field preferred.
• 5+ years of independent monitoring of clinical trials, including 2+ years in solid tumor trials.
• 1+ years of experience in early development trials.
• Solid tumor clinical trial experience required.
• Experience with GxP and oncology monitoring techniques, RBM.

Responsibilities

• Perform site management activities for oncology trials to ensure inspection readiness.
• Facilitate communication between trial team and investigative sites.
• Conduct remote and on-site monitoring visits to support data integrity and subject safety.
• Oversee and train less experienced CRAs to maintain monitoring quality.
• Document monitoring activities and manage site essential document collection.
• Support sites with local IRB/Ethics Committee submissions.
• Analyze Key Risk Indicators and implement corrective actions as needed.
• Lead site engagement initiatives and foster relationships with key oncology sites.

Skills

Independent monitoring

Solid tumor trials

Early development trials

GxP Expertise

Risk-Based Monitoring

Veeva experience

Site relationship building

Oncology monitoring

Education

Bachelor's degree in science

Tools

Veeva systems

Job description

For our client, we are seeking a Senior Clinical Research Associate to join the team of a leader in the Pharmaceuticals & Biotech space.

This role will support oncology clinical trials with a strong focus on site management, monitoring quality, and subject safety. The Senior Clinical Research Associate will partner closely with investigative sites and the broader clinical trial team to help ensure inspection readiness and compliant trial execution. This position also involves mentoring less experienced CRAs and using risk-based oversight to drive study performance.

Location: Remote - US based candidates only, no visa sponsorship available

Compensation: $110,520 – $138,150 annually

Responsibilities

• Perform site management activities for oncology clinical trials to ensure inspection readiness
• Facilitate communication between the clinical trial team and investigative sites
• Conduct remote and on-site monitoring visits to support data integrity and subject safety
• Oversee and train less experienced CRAs to maintain monitoring quality
• Document monitoring activities and manage site essential document collection
• Support sites with local IRB/Ethics Committee submissions
• Analyze Key Risk Indicators and implement corrective actions as needed
• Lead site engagement initiatives and foster relationships with key oncology sites

Qualifications

• Bachelor's degree in a scientific field preferred
• 5+ years of independent monitoring of clinical trials, including at least 2 years in solid tumor clinical trials
• 1+ years of experience in early development trials
• Solid tumor clinical trial experience required
• Experience with Veeva systems preferred
• Proven ability to develop site relationships and ensure compliance
• Expertise in GxPs and oncology monitoring techniques, including Risk-Based Monitoring

Benefits

• Comprehensive total rewards package supporting health and wellbeing
• Medical, dental, and vision coverage
• Retirement and pension plans
• Life assurance and disability coverage
• Employee assistance programmes and wellbeing resources
• Learning and development through structured training and career pathways

Our client is an equal opportunity employer. We encourage you to apply even if you don’t meet every qualification—your background could be exactly what this team needs.