Senior Clinical Project Manager

System One; Exton (PA); Remote; USD 120,000 - 160,000; Full time

Benefits offered by this job

Health and welfare benefits

401(k) plan

Job summary

System One is seeking a Senior Clinical Project Manager for a remote, full‑time role. You will lead complex clinical studies, manage budgets and vendors, and ensure regulatory compliance across sites.

The position reports to senior leadership and involves expanding site networks while delivering high-quality study reports. Ideal candidates have 10+ years in regulated clinical research, with experience in medical device projects, and strong leadership across cross‑functional teams.

Qualifications

• Bachelor’s degree required; scientific background preferred.
• 10+ years of experience in clinical research.
• Experience with medical device research, especially regulated projects.

Responsibilities

• Lead and manage complex studies from start-up to close-out.
• Drive budget management while leading complex projects.
• Perform vendor management and serve as the dotted line manager for CRAs and a junior PM.
• Ensure compliance with regulated project requirements, including pre-market IDE experience.
• Set up and add several new sites over the next few years.
• Complete medical writing study reports and perform quality audits.

Skills

Clinical research

Project management

Vendor management

Regulatory compliance

Leadership

Budget management

Education

Bachelor’s degree

Job description

Job Title: Senior Clinical Project Manager

Location: Remote

Type: Direct Hire

Hours: 40.0 hours per week

Overview

Seeking a highly organized and communicative Senior Clinical Project Manager to lead complex clinical studies, manage vendor relationships, and ensure regulatory compliance. The role involves setting up new clinical sites, overseeing project budgets, and delivering high-quality study reports. Ideal candidates will have extensive experience in regulated clinical research and proven leadership capabilities.

Responsibilities

• Lead and manage complex studies from start-up to close-out
• Drive budget management while leading complex projects
• Perform vendor management and serve as the dotted line manager for CRAs and a junior PM
• Ensure compliance with regulated project requirements, including pre-market IDE experience
• Set up and add several new sites over the next few years
• Complete medical writing study reports and perform quality audits

Requirements

• Bachelor’s degree required; scientific background preferred
• 10+ years of experience in clinical research
• Experience with medical device research, especially regulated projects
• Strong understanding of clinical research processes and vendor management
• Experience managing budgets and performing quality audits
• Experience setting up clinical sites is important
• Ability to manage complex projects and lead cross-functional teams

About System One

System One, and its subsidiaries including Joulé and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

Benefits

• System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

Equal Opportunity Statement

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.