Senior Cheminformatics Engineer: Makeable Space & Predict

Ginkgo Bioworks; Boston (MA); Presencial; USD 115 000 - 165 000; Tempo integral

Vantagens oferecidas por esta oferta de emprego

Stock awards

Medical, dental & vision coverage

401(k) employer contribution

Unlimited Paid Time Off

Resumo da oferta

Ginkgo Bioworks, Boston, MA, is seeking a Senior Engineer I, Cheminformatics to build and operate makeable chemical spaces and reaction-prediction workflows. You will drive enumeration, retrosynthesis, and data pipelines to connect design with synthesis in a production setting.

You will apply practical cheminformatics engineering with RDKit, Python, and scalable workflows, collaborating with internal chemists and engineers to deliver reliable results and well‑documented systems.

Qualificações

• Ph.D. in cheminformatics, computational chemistry, organic chemistry, medicinal chemistry, or a related field with 3+ years of experience; or MS with 6+ years; or BS with 9+ years.
• Strong practical experience in cheminformatics and reaction prediction, including retrosynthesis, reaction-condition prediction, or related workflows.
• Experience with reaction SMARTS, functional-group classification, molecular representations, and chemical structure data.
• Production experience with RDKit or equivalent toolkit.
• Experience with large chemical catalogs and understanding trade-offs in coverage, scale, and data quality.
• Strong Python skills and maintainable code writing.
• Familiarity with service-oriented software, Docker, env configuration, and data pipelines.
• Knowledge of medicinal-chemistry transformations and collaboration with synthetic chemists.
• Clear technical communication, documentation, provenance, and reproducibility.

Responsabilidades

• Develop and improve makeable chemical space through reaction enumeration and catalog handling.
• Integrate and evaluate retrosynthesis, synthetic‑feasibility, and reaction‑condition prediction workflows.
• Collaborate with chemists and engineers to deploy reliable computational workflows in production.

Conhecimentos

Cheminformatics

Python

RDKit

Reaction prediction

Formação académica

Ph.D. in cheminformatics or related field

MS in related field

Ferramentas

RDKit

Docker

SDF handling

Descrição da oferta de emprego

Ginkgo Bioworks, Boston, MA, is seeking a Senior Engineer I, Cheminformatics to build and operate makeable chemical spaces and reaction-prediction workflows. You will drive enumeration, retrosynthesis, and data pipelines to connect design with synthesis in a production setting.

You will apply practical cheminformatics engineering with RDKit, Python, and scalable workflows, collaborating with internal chemists and engineers to deliver reliable results and well‑documented systems.