Senior Biostatistician: Lead Stats Strategy & Insights

Denali Therapeutics Inc; South San Francisco (CA); On-site; USD 155,000 - 202,000; Full time

Benefits offered by this job

401k

Healthcare coverage

ESPP

Employee benefits package

Job summary

Denali Therapeutics Inc. in South San Francisco, CA seeks a senior Biostatistician to lead the statistical strategy and execution for core clinical programs. You will translate complex data into insights to inform neurodegenerative disease decisions, and oversee external vendors to ensure high-quality delivery.

You will conduct hands-on analyses, sample size estimation, and modeling, and present results to project teams and senior management, maintaining regulatory rigor and robust science.

Qualifications

• PhD in Statistics or Biostatistics with 3+ years in pharma/biotech.
• Demonstrated expertise in statistical methodology for pharma problems.
• Strong coding in R; familiarity with Unix/Linux, Git.

Responsibilities

• Leads development of clinical study deliverables, including SAS/analyses plans and reports.
• Ensures statistical integrity and regulatory compliance of deliverables.
• Conducts hands-on exploratory analyses, sample size estimation, and modeling.
• Interprets and presents data to internal teams and senior management.
• Oversees Biostatistics vendors and CROs for quality delivery.
• Maintains current expertise in statistics and regulatory landscape.

Skills

R

Markdown/Quarto

Git

Unix/Linux

Statistical methods

Cross-functional collaboration

Education

PhD in Statistics/Biostatistics

Master's in related discipline

Tools

CDISC

SDTM

ADaM

Job description

Denali Therapeutics Inc. in South San Francisco, CA seeks a senior Biostatistician to lead the statistical strategy and execution for core clinical programs. You will translate complex data into insights to inform neurodegenerative disease decisions, and oversee external vendors to ensure high-quality delivery.

You will conduct hands-on analyses, sample size estimation, and modeling, and present results to project teams and senior management, maintaining regulatory rigor and robust science.