Director of Biostatistics - Onsite Clinical Strategy Lead

Penfield Search Partners Ltd.; South San Francisco (CA); On-site; USD 235,000 - 300,000; Full time

Job summary

Penfield Search Partners Ltd. in South San Francisco, CA seeks an Associate Director or Director of Biostatistics to lead statistical analysis for clinical programs and direct project teams across development stages.

The role combines strategic leadership with hands-on statistical execution, including adaptive and Bayesian trial designs, regulatory input, and cross-functional collaboration. Onsite four days a week with a competitive salary and bonuses.

Qualifications

• PhD in Biostatistics/Statistics required with 8+ years of experience or MS with 10+ years.
• Strong understanding of clinical trial methodology and regulatory requirements.
• Ability to lead cross-functional teams and manage CROs and vendors.
• Excellent written and verbal communication for non-statistical stakeholders.

Responsibilities

• Independently lead biostatistical support for therapeutic programs and clinical studies across development phases.
• Develop statistical strategies aligned with development objectives and regulatory requirements.
• Collaborate with clinical and scientific teams to evaluate study design options and support data-driven decisions.
• Provide statistical input into study protocols, endpoints, sample size considerations, and evidence-generation plans.
• Develop and evaluate adaptive, Bayesian, and simulation-based trial designs where appropriate.
• Provide statistical expertise for studies with small sample sizes or rare diseases.
• Communicate statistical concepts clearly to cross-functional teams.

Skills

Leadership

Communication

Independent work

Data analysis

Cross-functional collaboration

Problem solving

Education

PhD in Biostatistics/Statistics

MS in Biostatistics/Statistics

Job description

Penfield Search Partners Ltd. in South San Francisco, CA seeks an Associate Director or Director of Biostatistics to lead statistical analysis for clinical programs and direct project teams across development stages.

The role combines strategic leadership with hands-on statistical execution, including adaptive and Bayesian trial designs, regulatory input, and cross-functional collaboration. Onsite four days a week with a competitive salary and bonuses.