Senior Bioanalytical Scientist: Ligand Binding & Cell Assays

Moderna Therapeutics; United States; Hybrid; USD 110,000 - 170,000; Full time

Benefits offered by this job

Competitive benefits

Hybrid in-office model

Job summary

Moderna is seeking an experienced Bioanalytical Scientist to develop, validate, and execute ligand-binding and cell-based assays supporting pharmacodynamic and immunogenicity endpoints for mRNA-derived proteins. You will test clinical samples under GcLP/GMP standards, generate robust data, and ensure regulatory compliance.

In a fast-paced, high-performing laboratory, you will document work using electronic notebooks, contribute to SOPs, and collaborate with Clinical Operations to define

Qualifications

• BA/BS in biological science with 5+ years industry Biotech/pharmaceutical/CRO experience or MS with 3+ years.
• Experience with Ligand Binding and/or Cell Based Assays is required.
• Experience in regulated environments (GLP, GcLP, GMP) is preferred.

Responsibilities

• Support development, optimization, and validation of ligand-binding and cell-based assays to evaluate pharmacodynamic and immunogenicity endpoints.
• Perform clinical sample testing across biological matrices in compliance with GcLP requirements using Thermo Watson LIMS.
• Deliver assay development and validation activities on schedule to support key program milestones.
• Maintain accurate experimental documentation using electronic lab notebooks.
• Review data and reports to ensure regulatory and Moderna quality expectations.

Skills

Ligand Binding Assays

Cell Based Assays

GcLP/GMP compliance

Regulatory documentation

Education

BA/BS in Biological Sciences

MS in Biological Sciences

Tools

Watson LIMS

LabVantage eLBN

Job description

Moderna is seeking an experienced Bioanalytical Scientist to develop, validate, and execute ligand-binding and cell-based assays supporting pharmacodynamic and immunogenicity endpoints for mRNA-derived proteins. You will test clinical samples under GcLP/GMP standards, generate robust data, and ensure regulatory compliance.

In a fast-paced, high-performing laboratory, you will document work using electronic notebooks, contribute to SOPs, and collaborate with Clinical Operations to define