Senior Bacterial Core Technician

Cape Fox Corporation; Maryland; On-site; USD 85,000 - 95,000; Full time

Job summary

An established industry player is seeking a Senior Bacterial Core Technician to support critical research at a prominent facility. This role involves conducting animal studies, performing in vitro testing against various bacteria, and contributing to the development of innovative therapeutic strategies. The ideal candidate will have a strong background in laboratory operations, animal manipulations, and data analysis, with a commitment to maintaining high standards of safety and compliance. Join a dynamic team dedicated to advancing scientific knowledge and improving public health through rigorous research and collaboration. If you are passionate about science and eager to make a meaningful impact, this opportunity is for you.

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life and Disability Insurance

Tuition Reimbursement

401K with Company Match

Paid Time Off

Company Holidays

Qualifications

• Experience in BSL-3 laboratory operations and animal studies.
• Proficient in in vitro testing and pharmacokinetics.

Responsibilities

• Conduct animal studies and perform in vitro MIC testing.
• Assist in laboratory management and ensure compliance with GLP regulations.

Skills

Animal Manipulation

In vitro Testing

Mass Spectrometry

Chromatography

Data Analysis

GLP Compliance

Education

Bachelor's Degree

Tools

HPLC MS/MS

Applied Biosystems Analyst

Excel

MultiQuant Software

Job description

Senior Bacterial Core Technician - (8001)

Cape Fox subsidiary Eagle Health, LLC is accepting resumes for a Senior Bacterial Core Technician to support the members at Ft. Detrick, Maryland. This position is contingent upon contract award.

Incumbents are encouraged to apply!

Responsibilities:

• BSL-3 laboratory operations and training in animal manipulations. Employee technicians shall perform approximately 5 animal studies in both the DTRA funded projects as well as contracted work.
• Perform in vitro Minimum Inhibition Concentration (MIC) testing of potential therapeutic compounds against Tier 1 bacteria. We currently utilize 30-strain diversity sets of Bacillus anthracis (anthrax), Yersinia pestis (plague), Francisella tularensis (tularemia), Burkholderia mallei (glanders), and Burkholderia pseudomallei (meliodosis), testing over 72 compounds per year against all 30 strains, in vitro.
• Participate in mouse, rat, rabbit, or other small animal studies, which include preparation of antibiotics for administration, administering drugs and vaccines, orally and by intraperitoneal, intramuscular, subcutaneous, and intravenous bolus injections. In addition, collect animal body fluids and remove tissues with all small animal studies executed. Upon execution of experiment all employee will perform animal health exams to ensure study remains in compliance with IACUC approved protocols.
• Participate in weekly lab meetings and assist in development and design with current and future in vitro and in vivo work. May be requested to present posters at 1 scientific conferences which may require work to be performed outside normal business hours.
• Participate in mouse, rat, rabbit, or other small animal BSL-2 pharmacokinetics and toxicology studies; to include preparation of antibiotics for administration; administering drugs and vaccines, followed by blood and tissue collection for pharmacokinetic or pharmacodynamic analyses.
• Support the in vivo pharmacology research program and contribute to the multidisciplinary research team to determine pharmacokinetics and pharmacodynamics relationships and efficacy of optimized leads.
• Shall assist with data analyses and drafting of reports for internal or external customers.
• Work with mass spectrometry, chromatography, HPLC MS/MS, specifically Sciex platforms coupled with Shimadzu HPLCs other and biophysical techniques to support in-process testing and characterization of biopharmaceutical products and impurities.
• Perform bioanalytical data acquisition, data analysis, and reporting of results using Applied Biosystems Analyst, Excel, and the Mass Spec Quantitation Software MultiQuant.
• Complete approximately 25 media/reagent preparations per year.
• Assist with approximately 5 animal challenges per year and 10 bacterial challenge preparations.
• Perform approximately 400 animal injections per year; 400 animal observations per year.
• Complete approximately 500 bacterial burdens in animal tissue per year.
• Perform approximately 500 small animal necropsies per year.
• Process approximately 300 animal gavage and approximately 125 animal blood collections per year.
• Place approximately 50 GFEBs orders per year for supplies and equipment.
• Maintain laboratories in BSL-2 and BSL-3.
• Perform or assist with BSAT Inventory Management weekly (to include applicable BSAT working stock material).
• Conduct or assist with Equipment Inventory Management twice a year in BSL-2 and BSL-3.
• Perform or assist with monthly Laboratory Management to include safety functions and chemical inventory.
• Review relevant literature monthly. May assist in the preparation standard operating procedures and manuscripts relating to their research efforts. The employee may be expected to present research findings at one scientific conference per year. Employee will present results in written and oral format publicly and internally as requested.
• Maintain a GLP training folder and be compliant with all GLP regulations when applicable.
• Directly contribute to the design, rationale, and be point-of-contact for 10 small animal studies to include drafting of a study plan and oversight of personnel scheduling.
• Contribute to study progress reports and scientific manuscripts to include statistical analysis, data compilation, figure preparation, and methods summary.
• Assist in establishing up to 28 new active material transfer agreements and cooperative research and development agreements with up to 8 pharmaceutical companies and/or universities. Employee shall maintain records of active agreements and collaborations.
• CS-PRP enrollment is required and will be held and maintained IAW the provisions in this contract and all applicable regulations.
• BPRP enrollment is required and will be held and maintained IAW the provisions in this contract and all applicable regulations.

Travel Requirements: 10 - 25%

Job Requirements:

• Bachelor's Degree
• CS-PRP enrollment is required and will be held and maintained IAW the provisions in this contract and all applicable regulations.
• BPRP enrollment is required and will be held and maintained IAW the provisions in this contract and all applicable regulations.
• Must be US Citizen per contract requirements

The salary range (or hiring range) for this exempt position has been established at: $85,000- $95,000.

The above salary range represents the company’s good faith and reasonable estimate of the range of possible compensation at the time of posting. In addition, we offer a variety of benefits including company holidays, paid time off, health insurance, dental insurance, vision insurance, life and disability insurance, tuition reimbursement, as well as 401K with company match. This job will be posted until filled or withdrawn.