Senior AWS Cloud Infrastructure Engineer (Remote)

Praxis Precision Medicines, Inc.

Northern (KY)

Hybrid

USD 125,000 - 150,000

Full time

2 days ago

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Job summary

Praxis Precision Medicines, Inc. is seeking a Senior Software Engineer to own AWS architecture for enterprise workloads, including multi-account foundations, landing zones, networking, and security baselines.

The role is remote with travel as needed; candidate builds secure, reliable systems and operates production infrastructure. You will work in TypeScript and Python, with on-call responsibilities, Infrastructure as Code (Pulumi/SST preferred), CI/CD with Bitbucket/GitHub Actions, and

Qualifications

Senior software engineer with hands-on experience building and operating production systems on AWS.
Strong full-stack capability in TypeScript and Python, APIs and cloud automation.
Deep experience with core AWS services in enterprise environments (IAM, VPC, EC2, S3, RDS, DynamoDB, CloudWatch, KMS, Config, GuardDuty).
Proven ability to design and operate AWS governance at scale, with multi-account strategy and security standards.
Experience with enterprise SSO, Microsoft Entra ID federation into AWS (SAML/OIDC, IAM Identity Center).
Experience with Infrastructure as Code and CI/CD tooling (Pulumi/SST, Terraform, AWS CDK).
On-call ownership, incident response, and ability to improve production readiness.

Responsibilities

Own and evolve AWS architecture for enterprise workloads, including multi-account foundations, landing zones, networking, security baselines, and shared platforms.
Establish and continuously improve AWS governance, including organizational structure, SCPs, tagging, cost controls, compliance, audit readiness, and durable operational standards.
Design and operate identity and access across AWS, including IAM, IAM Identity Center, and Microsoft Entra ID integrations for SSO, federation, role mapping, access reviews, and least-privilege access.
Build, harden, and operate AWS platforms and full-stack services using TypeScript and Python, including compute, containers, serverless, data stores, messaging, and cloud automation as needed.
Drive operational excellence across AWS platforms and workloads by building effective monitoring, alerting, dashboards, SLOs/SLIs, runbooks, incident response practices, and durable fixes to recurring problems.
Automate infrastructure and delivery through Infrastructure as Code—Pulumi and/or SST—with CI/CD using Bitbucket Pipelines and/or GitHub Actions.
Partner across engineering and IT to translate needs into secure, maintainable solutions, mentor other engineers, and move fast without breaking things.