Senior Analytical Lead, Early-Phase TIDES (Peptides & Oligos)

Eli Lilly and Company; Indianapolis (IN); On-site; USD 126,000 - 205,000; Full time

Job summary

Lilly, headquartered in Indianapolis, IN, seeks an experienced Senior Research Advisor / Research Advisor, Analytical Chemistry – TIDES, to lead analytical efforts for early-phase peptide and oligonucleotide programs. You will coordinate CMO/CRO activities, develop specifications, and integrate analytical strategy with cross-functional program plans.

This role focuses on GLP and GMP campaigns, IND/CTA documentation, and collaboration with Quality and Regulatory CMC to ensure Phase 1 readiness

Qualifications

• Ph.D. in analytical chemistry or related field with 2+ years of industry experience; or M.S. with 5+ years; or B.S. with 7+ years in analytical development.

Responsibilities

• Serve as the analytical lead for early-phase TIDES molecules, owning phase-appropriate control strategy for drug substance and drug product.
• Provide direction to external partners: define deliverables, approve method development and transfer, and oversee reports.
• Author and review CMC sections of INDs/CTAs; support responses to health authority questions.

Skills

Analytical chemistry

Chromatography

Mass spectrometry

Bioanalytical chemistry

Education

Ph.D. in analytical chemistry

Job description

Lilly, headquartered in Indianapolis, IN, seeks an experienced Senior Research Advisor / Research Advisor, Analytical Chemistry – TIDES, to lead analytical efforts for early-phase peptide and oligonucleotide programs. You will coordinate CMO/CRO activities, develop specifications, and integrate analytical strategy with cross-functional program plans.

This role focuses on GLP and GMP campaigns, IND/CTA documentation, and collaboration with Quality and Regulatory CMC to ensure Phase 1 readiness