Scientist, Synthetic Organic Chemistry

Beacon Hill; South San Francisco (CA); On-site; USD 140,000 - 150,000; Full time

Job summary

An established industry player is seeking a highly skilled scientist specializing in synthetic organic chemistry. This role involves collaborating with medicinal chemists and CRO partners to design and synthesize novel drug-like compounds. You will leverage your expertise to optimize potency and selectivity, ensuring candidates progress into clinical trials. Join a dynamic team where your contributions will directly impact the advancement of groundbreaking therapies. If you are passionate about innovation and eager to make a difference in the pharmaceutical landscape, this opportunity is for you.

Benefits

Medical Insurance

Vision Insurance

Qualifications

• Ph.D. in Synthetic Organic Chemistry with 1+ years of industry experience.
• Deep knowledge of organic synthesis and modern synthetic methodologies.
• Experience in purification and characterization of compounds.

Responsibilities

• Collaborate with medicinal chemists to design and synthesize drug-like compounds.
• Maintain detailed experimental records suitable for publications.
• Interface with CRO chemists to enhance productivity in synthetic activities.

Skills

Synthetic Organic Chemistry

Organic Synthesis

Problem-Solving

Communication Skills

Documentation Skills

Education

Ph.D. in Synthetic Organic Chemistry

Tools

NMR

LC-MS

Job description

Direct message the job poster from Beacon Hill

We are seeking a highly skilled and motivated scientist with expertise in synthetic organic chemistry to join our team in advancing the discovery and development of novel small molecules. As a key member of the synthetic chemistry group, you will collaborate closely with medicinal chemists and external CRO partners to design, synthesize, and characterize drug-like compounds optimized for potency, selectivity, pharmacokinetics, and efficacy, with the goal of advancing candidates into human clinical trials.

Required Qualifications:

Educational Background:

• Ph.D. in Synthetic Organic Chemistry with 1+ years of experience in the biotechnology or pharmaceutical industry, specifically within a chemistry department.

Technical Expertise:

• Deep knowledge of organic synthesis, with familiarity with current literature and modern synthetic reactions and methodologies.
• Proven ability to design robust, multi-step synthetic routes that allow for late-stage diversification.
• Strong problem-solving skills with the creativity to troubleshoot and optimize complex reactions independently.
• Experience running reactions in parallel to efficiently deliver final compounds in batches.
• Proficiency in medium-scale synthesis to prepare key intermediates.
• Skilled in the purification and characterization of intermediates and final compounds using modern techniques (e.g., NMR, LC-MS).

Documentation and Reporting:

• Ability to maintain high-quality, detailed experimental records in electronic notebooks (e-notebooks), ensuring data is suitable for publications and patent filings.

Collaboration and Communication:

• Team-oriented, with strong interpersonal skills to exchange information effectively and contribute to a collaborative work environment.
• Scientific curiosity and enthusiasm for contributing to a dynamic research setting.
• Excellent verbal and written communication skills, capable of presenting rationale, key data, challenges, and accomplishments clearly to internal teams and external collaborators (e.g., CROs).

CRO Interaction:

• Demonstrated ability to interface with and guide CRO chemists to achieve high efficiency and productivity in synthetic activities.

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Contract

Job function

• Job function

  Science and Research

• Industries

  Pharmaceutical Manufacturing and Biotechnology Research

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Inferred from the description for this job

Medical insurance

Vision insurance

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