Scientist/Senior Scientist, Oligonucleotide Sciences Analytical Chemistry

Women In Bio; Cambridge (MA); On-site; USD 80,000 - 110,000; Full time

Job summary

An innovative company is seeking a skilled Scientist in Oligonucleotide Analytical Chemistry to join their dynamic team. This role offers the chance to lead the development of advanced analytical methods and contribute to the quality control of cutting-edge oligonucleotide therapeutics. You will play a pivotal role in building a state-of-the-art analytical lab while collaborating with cross-functional teams to enhance pipeline technologies. Ideal candidates will have a strong background in mass spectrometry and analytical chemistry, with opportunities for mentoring junior scientists. Join this exciting journey to advance the future of therapeutics and make a meaningful impact in the field.

Qualifications

• 5+ years of experience in analytical chemistry with a focus on oligonucleotides.
• Strong background in mass spectrometry and method troubleshooting.

Responsibilities

• Develop and deploy analytical methods for synthetic oligonucleotides.
• Collaborate with project teams and support analytical investigations.

Skills

Mass Spectrometry

Analytical Chemistry

LC/MS Method Development

Data Analysis

Communication Skills

Education

Bachelor's Degree

Master's Degree

PhD

Tools

LC/MS-MS

Job description

Are you looking for a collaborative analytical chemistry role that allows you to meaningfully contribute to GSK’s pre-clinical oligonucleotide pipeline? If so, this role could be an ideal opportunity to explore.

As Scientist, Oligonucleotide Analytical Chemistry, you and your team will play an important role in the analysis and quality control of GSK’s preclinical oligonucleotide therapeutics pipeline. You will develop and execute advanced analytical methods for a diversity of synthetic oligonucleotide modalities to help accelerate GSK’s pipeline and platform technology ambitions.

Key Responsibilities

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

• Take part in the buildout of GSK’s state-of-the-art analytical chemistry lab in our growing Oligonucleotide Sciences group
• Develop and deploy robust analytical methods to characterize novel synthetic oligonucleotides in low-and high-throughput settings
• Use advanced LC/MS-MS capabilities to fully characterize novel synthetic oligonucleotides and related species
• Help design and manage key data pipelines
• Collaborate internally and externally, representing Oligonucleotide Sciences Analytical Chemistry on project teams
• Support analytical investigations, including root cause analysis, in collaboration with cross-functional teams
• Participate in hiring, mentoring and training of junior team members, ensuring knowledge transfer and capability development
• May be responsible for the management of junior scientists or small team

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• BS with 5+ years, MS with 3+ years, of relevant experience.
• Experience with modern mass spectrometry methodology and data analysis as it pertains to oligonucleotides
• Strong background in LC/MS method development and method troubleshooting.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• PhD with relevant experience
• 1+ years of experience managing laboratory scientists
• Experience with high-throughput LC/MS(-MS) data acquisition and analysis
• Experience with the LC/MS(-MS) analysis of small molecules and/or biologics
• Exposure to modern LC/MS(-MS) data analysis platforms as it pertains to oligonucleotides
• Exposure to other aspects of oligonucleotide drug discovery & development, including biology, bioanalysis, DMPK, delivery, etc.
• Excellent communication, presentation, and documentation skills
• Familiarity working in cross-functional matrix project teams