Scientist - Research and Development

LanceSoft Inc; Malvern (Chester County); On-site; USD 80,000 - 100,000; Full time

Job summary

A leading company in the biotechnology sector seeks a Scientist 2 specializing in Research and Development for CAR-T cell therapies. The position involves assay method development, testing across therapy programs, and maintaining cell cultures. Candidates should hold degrees in relevant scientific fields and have laboratory experience with plate-based assays. This role offers competitive hourly pay from $35 to $38, emphasizing strong analytical and communication skills.

Qualifications

• Master's or bachelor's degree with relevant experience in cell biology or related field.
• Experience with immortalized cell culture (adherent and suspension cells).
• Strong analytical problem solving, planning, and organizational skills.

Responsibilities

• Plan and execute ELISA, AlphaLISA, and other plate-based assays for CAR-T cell therapies.
• Maintain healthy cultures of immortalized cell lines.
• Keep an organized inventory of reagent stocks and maintain electronic lab notebook practices.

Skills

Analytical problem solving

Planning

Organizational skills

Communication

Interpersonal skills

Education

Master's degree in cell biology, immunology, biological science, or related field

Bachelor's degree in an appropriate scientific discipline

Tools

ELISA

AlphaLISA

MSD

Kinexa

Biacore

Job description

Job title: Scientist 2 - Research and Development
Location: Malvern PA 19355
Duration: 06/30/2025 to 06/29/2027

Pay Range: $35.00/HR - $38.00/HR

Description:

Scientist 2, Analytical Development, Advanced Therapies, Functional Potency Method Development The Advanced Therapies, Functional Potency Method Development group is seeking an energetic, highly motivated scientist to support CAR-T cell therapies. The contactor will serve as a specialist in binding assay method development and assay validation.

Primary responsibilities:
• Plan and execute ELISA, AlphaLISA, luciferase reporter, and other plate-based assays • Test samples across all CAR-T cell therapy programs
• Maintain healthy cultures of immortalized cell lines according to requirements
• Help keep a large inventory of reagent stocks maintained and well organized • Maintain good electronic lab notebook (ELN) practices to ensure proper data documentation
• Demonstrate excellent communication and interpersonal skills
• The candidate is expected to work effectively in a team environment and well as contributing individually to meet project objectives and timelines.
• Other duties to be assigned as necessary.

Required:

• Master’s degree with at least 1-2+ years of experience or bachelor's degree with at least 3-4+ years’ experience in an appropriate scientific discipline (cell biology, immunology, biological science, or related field).
• Prior experience with immortalized cell culture (adherent and suspension cells)
• Prior experience with cell counting
• Prior experience running plate-based methods (e.g. ELISA, AlphaLISA, MSD, and luciferase reporter assays)
• Strong analytical problem solving, planning and organizational skills Preferred: • Hands-on experience with CAR-T or other cell and gene therapy products
• Experience with co-culture functional assays in immuno oncology
• Experience in analytical method development
• Experience in analytical method qualification and validation
• Experience with Kinexa and Biacore
• Experience with MSD
• Knowledge of ICH (Q2)R2 standards

Top Three Skills: Bachelor of Science, ELISA/AlphaLISA Experience, Cell Culture Experience

Top Three Skills: Bachelor of Science, Plate-based method (ELISA/AlphaLISA) Experience, Cell Culture Experience