Scientist, Ophthalmology

Regeneron Pharmaceuticals, Inc (USA); Village of Tarrytown (NY); On-site; USD 94,000 - 153,000; Full time

Job summary

Regeneron Pharmaceuticals, Inc. in Tarrytown, NY seeks an independent bench Scientist to join the Ophthalmology group, developing in vitro assays and mouse models to study ocular autoimmunity and evaluate therapeutic candidates.

You will perform ELISA, MSD, Luminex, RT-PCR, and flow cytometry on mouse and human samples, isolate tissues, and contribute to data analysis and study reports; onsite work with cross-functional collaboration is expected.

Qualifications

• BS/MS in Biology or related field with 4–5 years lab experience.
• Strong knowledge of molecular and cellular biology.
• Experience with tissue culture and flow cytometry.
• Experience with in vitro modification of cell lines and primary mouse/human cells.

Responsibilities

• Design, plan, and perform in vitro and in vivo studies using cell lines and mouse models.
• Run ELISA/MSD/Luminex, RT-PCR, and flow cytometry.
• Isolate tissues and cells from mouse and human samples for characterization.
• Develop and execute in vitro cell-based functional assays.
• Work with mice including dosing and tissue collection.

Skills

Molecular biology

Cell biology

Flow cytometry

RT-PCR

Mouse handling

Education

BS/MS in Biology

Tools

ELISA

MSD

Luminex

Job description

Build our future together: At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking an independent and highly motivated bench Scientist to join our Ophthalmology group, supporting the development of therapeutics for ocular and autoimmune diseases. In this role, you will engage in innovative research as part of our discovery efforts, developing new in vitro assays and models to elucidate pathways involved in ocular autoimmunity and evaluating therapeutic candidates, while collaborating closely with teams across the organization. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:

Location: Tarrytown, NY Work model/flexibility: Onsite

Discover your role:

• Design, plan, and perform in vitro and in vivo studies using cell lines and mouse models to investigate, validate, and screen therapeutic targets
• Run ELISA/MSD/Luminex, RT-PCR, and flow cytometry using mouse/human serum and tissue
• Isolate tissues and cells from mouse and human samples for further functional and phenotypic characterization
• Design and/or execute in vitro cell-based functional assays using primary or engineered cells
• Work with mice, including antibody dosing through various routes, interim bleeds, and tissue collection/processing
• Develop new methods or technologies to troubleshoot experiments
• Analyze data and communicate findings to peers and management at group and cross-functional meetings
• Write protocols and study reports, maintaining accurate electronic records

This role requires:

• BS/MS degree in Biology, Cell Biology, Immunology, or a related field, with 4-5 years of experience working in a laboratory setting
• Strong knowledge of molecular and cellular biology
• Experience with tissue culture (maintenance of transformed and primary cells), in vitro and ex vivo cell-based assays, and multicolor flow cytometry
• Experience with in vitro modification of cell lines and primary mouse and human cells
• Training in proper handling and care of mice, and collection of blood and tissue samples

Preferred:

• expertise in immunology or ophthalmology
• experience with mouse models of inflammatory/autoimmune diseases

Benefits and Compensation

• Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits.
• Salary Range (annually) $93,900.00 - $153,300.00
• Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law.

Many roles are required to be performed on-site.

Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for over 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to nine FDA-approved treatments and numerous product candidates in development, almost all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurology, infectious diseases and rare diseases.

Regeneron is also proud of award-winning culture of innovation, being recognized as a Great Place to Work in 2021, Fast Company’s Best Workplace for Innovators in 2020, and Forbes JUST companies in 2020, among others.