Scientist, Non-Viral Gene Editing Platforms

Bristol-Myers Squibb Company; Seattle (WA); On-site; USD 123,000 - 149,000; Full time

Benefits offered by this job

Flexible Time Off

11 paid holidays

Stock options

Job summary

Bristol Myers Squibb Company is seeking a Scientist to advance non-viral gene editing for CAR-T cell platforms in Seattle, WA. You will independently execute experiments, optimize editing strategies, and contribute to multidisciplinary teams advancing next-generation therapies.

The role emphasizes detailed data analysis, ELN documentation, and collaboration within fast-paced, cutting-edge research environments. Competitive compensation and comprehensive benefits are offered.

Qualifications

• Bachelor’s Degree or higher with 5+ years of experience in biology or biotech.
• Master’s Degree with 3+ years of experience; Ph.D. preferred for advanced roles.
• Ph.D. or equiv. degree in Life Sciences strongly preferred.

Responsibilities

• Execute experiments in the lab and record ELN entries.
• Optimize base ex vivo editing platform and develop in vivo non-viral gene delivery (e.g., lipid nanoparticles).
• Routinely generate CAR-T cells including non-viral gene editing, expansion, and cryopreservation.
• Characterize engineered CAR-T cells via flow cytometry and molecular analyses.
• Analyze data, troubleshoot, and communicate results to cross-functional teams.

Skills

CRISPR editing

Flow cytometry

T cell culture

Data analysis

Team collaboration

ELN documentation

Non-viral delivery

Molecular biology

Benchling

Geneious

Education

Bachelor's Degree

Master’s Degree

Ph.D. or equivalent

Tools

Benchling

Geneious

Job description

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

Position Responsibilities

• Spends a majority of the time working in the lab independently executing experiments and recording detailed ELN entries
• Works diligently within the team to optimize base ex vivo editing platform and implement new technologies for continuous improvement and next-gen in vivo platform development (e.g., lipid nanoparticles)
• Routinely generates CAR-T cells including non-viral gene editing, expansion, and cryopreservation of engineered cells
• Thoroughly characterizes engineered CAR-T cells including phenotypic analysis via flow cytometry, in vitro cytotoxicity assays (e.g., Incucyte), and genomic DNA extraction for downstream molecular analysis
• Independently analyses and interprets experimental data, experience with large and complex datasets a plus
• Actively troubleshoots routine problems and initiatives related to continuous improvement or development of new approaches / technologies
• Proactively communicates and aligns with team members to achieve results and support cross-functional activities
• Generates key data to support decisions that impact the larger team
• Present findings in multidisciplinary meetings, logically explaining complex scientific concepts and clearly highlighting key messages
• May represent department or team on program/project team or sub-team

Experience

Basic Qualifications:

• Bachelor’s Degree
• 5+ years of academic and / or industry experience

Or

• Master’s Degree
• 3+ years of academic and / or industry experience

Or

• Ph.D. or equivalent advanced degree in the Life Sciences

Preferred Qualifications:

• Hands-on experience with gene editing technologies (CRISPR/Prime editing preferred)
• Experience with in vivo non-viral gene delivery platforms (including non-cell therapy applications)
• Strong knowledge of molecular biology and prior experience with DNA design tools such as Benchling, Geneious, etc.
• Experience culturing T cells including aseptic technique, T cell activation, and maintenance of primary cell cultures
• Experience with multi-color flow cytometry including complex panel design and multi-parameter data analysis (FlowJo)
• Ability to effectively multi-task, independently organize time, and can develop timelines and deliver results accordingly
• Demonstrated ability to work within a team and thrive in a fast-paced and ever-changing environment
• Detail oriented with excellent verbal and written communication skills and careful documentation (prior ELN experience a plus)

Compensation Overview

Seattle - WA: $122,810 - $148,814

The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.

Benefits

Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).

U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year.

Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays.

Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day.

U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits

How We Work

Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail] . Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If this posting is missing required information required by local law or incorrect, contact BMS at [e-mail] with the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.

R1607442 : Scientist, Non-Viral Gene Editing Platforms