Scientist, Neuromuscular Research

Biogen; Cambridge (MA); On-site; USD 110,000 - 170,000; Full time

Benefits offered by this job

Medical, Dental, Vision

401(k) plan

Employee stock purchase plan

Tuition reimbursement

Job summary

Biogen is seeking a highly motivated Scientist to join our neuromuscular research group in Cambridge, MA. The role focuses on neuromuscular biology, biochemistry, and molecular biology to elucidate disease mechanisms and identify therapeutic targets, contributing to potential treatment strategies.

You will design experiments, develop iPSC-derived and human cell models, and evaluate therapeutics in collaboration with internal teams and external partners.

Qualifications

• PhD with 0-2+ years of relevant academic or industry experience in muscle biology, physiology, or a related field.
• Strong scientific and technical background in muscle biology, disease pathophysiology, and translational research.
• Demonstrated hands-on experience with iPSC-derived and primary human myotube and cardiomyocyte culture, in vivo muscle function assessment, biochemistry and molecular biology techniques; statistical analysis using GraphPad Prism.

Responsibilities

• Independently design, execute, analyze, and interpret experiments supporting neuromuscular research programs.
• Develop and optimize molecular and cellular assays in iPSC-derived and primary human skeletal and cardiac disease models to assess therapeutic activity and mechanism of action.
• Characterize muscle disease relevant phenotypes in rodent models.
• Present data clearly and concisely in team meetings and other cross-functional forums.
• Collaborate with internal teams and external partners to facilitate research progress.

Skills

Muscle biology

Neuromuscular disorders

Molecular biology

Biochemistry

Data analysis

Presentation skills

Education

PhD in muscle biology

Tools

GraphPad Prism

iPSC culture

Rodent models

Job description

About This Role

We are seeking a highly motivated Scientist to join our dynamic neuromuscular research group and advance research programs focused on neuromuscular disorders. The ideal candidate will leverage expertise in neuromuscular biology, biochemistry and molecular biology to investigate disease mechanisms, identify novel therapeutic targets, and evaluate candidate therapeutics. As part of a collaborative team, your work will have a direct impact on understanding and potentially treating neuromuscular disorders, fitting seamlessly into the broader mission of our organization to innovate and improve patient outcomes.

About This Role

We are seeking a highly motivated Scientist to join our dynamic neuromuscular research group and advance research programs focused on neuromuscular disorders. The ideal candidate will leverage expertise in neuromuscular biology, biochemistry and molecular biology to investigate disease mechanisms, identify novel therapeutic targets, and evaluate candidate therapeutics. As part of a collaborative team, your work will have a direct impact on understanding and potentially treating neuromuscular disorders, fitting seamlessly into the broader mission of our organization to innovate and improve patient outcomes.

What You’ll Do

• Independently design, execute, analyze, and interpret experiments supporting neuromuscular research programs.
• Develop and optimize molecular and cellular assays in iPSC-derived and primary human skeletal and cardiac disease models to assess therapeutic activity and mechanism of action.
• Characterize muscle disease relevant phenotypes in rodent models.
• Present data clearly and concisely in team meetings and other cross-functional forums.
• Collaborate with internal teams and external partners to facilitate research progress.

Required Skills

• PhD with 0-2+ years of relevant academic or industry experience in muscle biology, physiology, or a related field.
• Strong scientific and technical background in muscle biology, disease pathophysiology, and translational research.
• Demonstrated hands-on experience with the following techniques:
  • iPSC-derived and primary human myotube and cardiomyocyte culture
  • In vivo muscle function assessment, including evoked force measures, treadmill and other relevant endpoints in neuromuscular disease models.
  • Biochemistry and molecular biology techniques
  • Statistical analysis using GraphPad Prism or similar data analysis software
• Ability to independently design, execute and trouble shoot experiments
• Excellent presentation and communication skills

Preferred Skills

• Strong scientific background in muscle biology and/or genetic neuromuscular disorders such as DMD and DM1.
• Direct experience with RNA therapies, antisense oligonucleotides, LNP
• Strong track record of scientific publications and presentations

Job Level: Professional

Additional Information

The base compensation range for this role is: -

Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.

Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.

Benefits

• Medical, Dental, Vision, & Life insurances
• Fitness & Wellness programs including a fitness reimbursement
• Short- and Long-Term Disability insurance
• A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
• Up to 12 company paid holidays + 3 paid days off for Personal Significance
• 80 hours of sick time per calendar year
• Paid Maternity and Parental Leave benefit
• 401(k) program participation with company matched contributions
• Employee stock purchase plan
• Tuition reimbursement of up to $10,000 per calendar year
• Employee Resource Groups participation

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about Biogen.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.