Scientist, mRNA Formulation

GSK; Cambridge (MA); On-site; USD 90,000 - 150,000; Full time

Benefits offered by this job

Health insurance

Pension plan

Annual bonus

Shares program

Paid holidays

Vacation

Paid caregiver/parental and medical p

Job summary

GSK in Cambridge, MA is seeking a Scientist focused on mRNA formulation to design and develop innovative delivery systems supporting vaccine and medicine discovery programs. You will lead laboratory studies, collaborate across disciplines, and contribute to product understanding and accelerated development.

This role requires a BS/MS/PhD in a related field with hands-on mRNA‑LNP formulation experience. On-site work only; GSK offers a strong compensation package including annual bonus,

Qualifications

• BS, MS, or PhD in Pharmaceutical Sciences, Pharmaceutics, Chemical Engineering, Chemistry, Biochemistry, Biomedical Engineering, or a related scientific discipline (BS and a minimum of 5 years of relevant experience, MS and a minimum of 3 years of relevant experience, or PhD and 0 years of relevant experience).
• A minimum of 1 year of hands-on laboratory experience developing and evaluating mRNA‑LNP formulations or other nucleic acid delivery systems.

Responsibilities

• Design, prepare, and evaluate mRNA formulations and delivery systems, including lipid nanoparticle (LNP) platforms, to assess stability, compatibility, encapsulation efficiency, and performance.
• Develop and execute formulation studies, stability studies, and stress studies to advance mRNA vaccine and therapeutic programs.
• Characterize physicochemical properties of mRNA formulations using analytical techniques such as dynamic light scattering (DLS), zeta potential, chromatography, and thermal analysis.
• Analyze and interpret experimental data, identify formulation risks and opportunities, and recommend strategies to improve product quality, stability, and performance.
• Collaborate closely with analytical, process development, regulatory, and quality teams to support project goals and advance development programs.
• Maintain accurate laboratory records, prepare study reports, and communicate scientific findings through presentations and technical documentation.
• Maintain the drug product laboratory space in a safe, organized, and inspection‑ready manner.
• Support troubleshooting and problem‑solving efforts to address formulation challenges.

Skills

Biotechnology

Cell Biology

Cross-Functional Teamwork

Data Quality

Following Instructions

Interpersonal Communication

Lab Maintenance

Life Science

Matrix Leadership

Proper Documentation

Scientific Presentations

Scientific Research

Scientific Writing

Education

BS/MS/PhD in Pharmaceutical Sciences or related field

Tools

Laboratory Techniques

Job description

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programs, pension plan membership, and shares and savings programme. We embrace modern work practices; our Performance with Choice programme offers a remote or hybrid working model, empowering you to find the optimal balance between remote and in-office work. Discover more about our company-wide benefits and life at GSK on our webpage Life at GSK | GSK Find out more about GSK and R&D: Our approach to R&D Scientist, mRNA Formulation Join GSK as a Scientist focused on mRNA formulation, where you will design and develop innovative mRNA delivery systems that support our vaccine and medicine discovery programs. Working closely with colleagues across disciplines, you will lead laboratory studies that enhance product understanding and accelerate development. We value curious, motivated scientists who take ownership, communicate clearly, and thrive in a collaborative environment. This role offers you a chance to grow your skills, make a meaningful impact, and contribute to GSK’s mission of uniting science, technology, and talent to get ahead of disease together.

This role is located Cambridge, MA in the United States and requires working on-site. Hybrid or remote work options are not available for this position.

Responsibilities

• Design, prepare, and evaluate mRNA formulations and delivery systems, including lipid nanoparticle (LNP) platforms, to assess stability, compatibility, encapsulation efficiency, and performance.
• Develop and execute formulation studies, stability studies, and stress studies to advance mRNA vaccine and therapeutic programs.
• Characterize physicochemical properties of mRNA formulations using analytical techniques such as dynamic light scattering (DLS), zeta potential, chromatography, and thermal analysis.
• Analyze and interpret experimental data, identify formulation risks and opportunities, and recommend strategies to improve product quality, stability, and performance.
• Collaborate closely with analytical, process development, regulatory, and quality teams to support project goals and advance development programs.
• Maintain accurate laboratory records, prepare study reports, and communicate scientific findings through presentations and technical documentation.
• Maintain the drug product laboratory space in a safe, organized, and inspection‑ready manner.
• Support troubleshooting and problem‑solving efforts to address formulation challenges.

Basic Qualifications

• BS, MS, or PhD in Pharmaceutical Sciences, Pharmaceutics, Chemical Engineering, Chemistry, Biochemistry, Biomedical Engineering, or a related scientific discipline (BS and a minimum of 5 years of relevant experience, MS and a minimum of 3 years of relevant experience, or PhD and 0 years of relevant experience).
• A minimum of 1 year of hands‑on laboratory experience developing and evaluating mRNA‑LNP formulations or other nucleic acid delivery systems.

Preferred Qualifications

• Advanced degree (Master’s or PhD) in a relevant discipline.
• Experience with vaccine formulation, protein biologics, nanoparticle delivery systems, or other advanced drug delivery technologies.
• Experience designing and executing formulation studies, stability studies, and other drug product development experiments.
• Practical knowledge of lipid nanoparticle formulation development and characterization.
• Knowledge of high‑throughput formulation screening and stability study design.
• Familiarity with process development, scale‑up considerations and manufacturing handoffs.
• Familiarity with characterization techniques used to evaluate formulation quality, such as dynamic light scattering, zeta potential measurement, or chromatography.

Skills

• Biotechnology
• Cell Biology
• Cross-Functional Teamwork
• Data Quality
• Following Instructions
• Interpersonal Communication
• Lab Maintenance
• Life Science
• Matrix Leadership
• Proper Documentation
• Scientific Presentations
• Scientific Research
• Scientific Writing

Available Benefits

• health care and other insurance benefits (for employee and family)
• retirement benefits
• paid holidays
• vacation
• paid caregiver/parental and medical leave

If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $89,925 to $149,875.

Why GSK?

Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

Accommodations

If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at [e-mail]

Equal Opportunity Employer

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

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