Scientist, In Vivo Pharmacology

Bristol Myers Squibb; Cambridge (MA); On-site; USD 128,000 - 156,000; Full time

Benefits offered by this job

Health insurance

401(k) plan

Paid time off

Job summary

Bristol Myers Squibb is seeking a Scientist in In Vivo Pharmacology to support oncology and immunology discovery programs in Cambridge, MA. You will design, execute, analyze, and interpret preclinical in vivo studies to advance candidates from target validation to selection.

The role requires strong pharmacology, immunology, or oncology background, plus expertise in in vivo models, rodent handling, and IVIS imaging. Collaboration with cross-functional teams is essential.

Qualifications

• Bachelor’s Degree in Life Sciences (or higher) required.
• Master’s Degree in Life Sciences preferred; PhD highly desirable.
• PhD or equivalent advanced degree in Life Sciences required or preferred depending on level.

Responsibilities

• Design and interpret in vivo studies in cancer and immune-related models.
• Perform and oversee in vivo studies including dosing, disease induction, and sample collection.
• Develop strategies to evaluate pharmacodynamics, efficacy, and mechanism-of-action.

Skills

In vivo pharmacology

Oncology

Immunology

Rodent handling

IVIS imaging

Data analysis

Education

PhD in Life Sciences

Master’s Degree in Life Sciences

Bachelor’s Degree

Tools

GraphPad Prism

Excel

Job description

Working with Us

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Position Summary

Bristol Myers Squibb is seeking a highly motivated Scientist to join the In Vivo Pharmacology group supporting Oncology and Immunology discovery programs. The successful candidate will play a key role in the design, execution, analysis, and interpretation of preclinical in vivo studies to evaluate novel therapeutic candidates. This position requires a strong scientific background in pharmacology, immunology, and/or oncology, as well as the ability to independently drive experimental strategies and collaborate within multidisciplinary discovery teams to advance programs from target validation through candidate selection.

Position Responsibilities

In the role as a Scientist within In Vivo Pharmacology, the ideal candidate will:

In Vivo Study Execution (Oncology & Immunology)

• Design and interpret in vivo studies in murine models of cancer and immune-mediated diseases.

• Perform and oversee in vivo studies, including compound administration, disease induction, tumor implantation, immune cell transfers, longitudinal sampling, and animal monitoring.

• Develop experimental strategies to evaluate pharmacodynamic, efficacy, mechanism-of-action, and combination therapy hypotheses.

• Independently operate and apply imaging technologies, including IVIS, to support efficacy and mechanistic studies.

• Troubleshoot technical and scientific challenges and develop solutions to improve study outcomes.

• Contribute to the optimization and development of novel in vivo models and experimental workflows.

Data Analysis & Reporting

• Analyze and interpret complex datasets using GraphPad Prism, Excel, and other data analysis tools.

• Integrate in vivo, pharmacodynamic, biomarker, and mechanistic data to generate actionable scientific insights.

• Maintain accurate and timely electronic laboratory notebook (ELN) documentation.

• Prepare and present study results, scientific reports, and project updates to cross-functional teams and leadership.

• Contribute to scientific publications, technical reports, presentations, and regulatory documentation as appropriate.

Cross-Functional Collaboration

• Serve as an in vivo pharmacology representative on Oncology and Immunology project teams.

• Partner with external collaborators and contract research organizations (CROs) to support study execution and data interpretation.

• Contribute scientific insights to project strategy, portfolio discussions, and candidate advancement decisions.

Laboratory Operations & Compliance

• Ensure compliance with BMS policies, IACUC regulations, and animal welfare standards.

• Maintain lab supplies, equipment, and study materials.

• Participate in continuous improvement of in vivo models and workflows.

Experience

Basic Qualifications:

• Bachelor’s Degree

Or

• Master’s Degree

Or

• Ph.D. or equivalent advanced degree in the Life Sciences

Preferred Qualifications:

• PhD in Pharmacology, Immunology, Oncology, Cell Biology, or a related life science discipline; or

• MS with 3+ years, or BS with 5+ years of relevant industry experience in in vivo pharmacology.

• Strong scientific expertise in preclinical in vivo pharmacology required.

• Demonstrated experience designing, executing, and interpreting studies in oncology and/or immunology disease models required.

• Hands-on experience with rodent handling, dosing techniques, and biological sample collection required.

• Experience with tumor models, immune-mediated disease models, or both required.

• Proficiency with IVIS imaging and associated data analysis required.

• Strong understanding of experimental design, statistics, and data interpretation.

• Excellent problem-solving skills and scientific curiosity.

• Strong written and verbal communication skills with the ability to effectively present scientific findings.

• Ability to manage multiple priorities and work effectively in a collaborative, fast-paced research environment.

• Industry experience in biotech or pharmaceutical R&D desired.

• Experience working in matrixed, cross-functional teams desired.

• Familiarity with imaging techniques, biomarkers, or molecular assays desired.

#LI-Onsite

Compensation Overview:

Cambridge - MA - US: $128,380 - $155,571

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.

Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:

• Health Coverage: Medical, pharmacy, dental, and vision care.

• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).

• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.

Work-life benefits include:

Paid Time Off

• US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)

• Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays

Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

_ *Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at [e-mail]. Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response. Inquiries related to the status of your application should be directed to Chat with Ripley.

R1605651 : Scientist, In Vivo Pharmacology