Scientist, Immunology

BioSpace; Monrovia (CA); On-site; USD 120,000 - 175,000; Full time

Benefits offered by this job

Stock option plan

3% retirement contribution

Fully paid health, dental, and vision

Above-market life insurance

Disability coverage

Job summary

Terray Therapeutics is seeking a motivated immunologist to join our cell assay team. This full-time onsite role will design experiments to define mechanism of action of Terray hits, optimize assays, and support hit-to-lead progression.

The candidate should have a strong immunology background and hands-on experience with diverse cellular techniques. You will work with a multidisciplinary team to profile on- and off-target activity, manage CROs as needed, and help advance our EMMI platform's drug

Qualifications

• PhD with 3+ years small molecule drug discovery experience in immunology.
• Or MSc with 10+ years in small molecule drug discovery industry.
• Strong background in immunology and immune signaling pathways.
• Hands-on experience with cell culture and cell-based assays.
• Experience establishing robust IC50 assays and dose-response curves.

Responsibilities

• Design experiments to confirm mechanism of action of small molecule hits in cells.
• Independently develop, optimize, and run cell-based assays to profile hits.
• Adapt assays for medium/high-throughput screening and IC50 generation.
• Manage CROs for reagent development and in vitro testing as needed.
• Analyze data and communicate results in project team meetings.
• Interface with chemists and computational scientists to drive decisions.
• Support organization of lab and equipment as needed.

Skills

Immunology

Cell culture

Flow cytometry

qPCR

RNAseq

ELISA

Intracellular techniques

Education

PhD in immunology/molecular/cell biology

MSc with 10+ years in small molecule drug discovery

Tools

Luminex

MSD

Western blot

Job description

Company Overview:

Terray Therapeutics is a venture-backed biotechnology company where scientists and engineers build together to transform how small-molecule drugs are discovered and developed. By combining our nanotechnology, experimental science, machine learning, and automation, we leverage Terray’s ability to generate and learn from scale proprietary chemical data to discover novel medicines for patients in need.

At Terray, you will work alongside pioneers and experts in artificial intelligence, chemistry, drug discovery, automation, and nanotechnology in deeply interconnected workflows where computational and experimental teams continuously learn from one another. Our platform, EMMI (Experimentation Meets Machine Intelligence), powers iterative cycles of molecular design and wet-lab experimentation that rapidly improve our understanding of biochemical interactions and guide the next generation of discoveries.

Our teams support both an internal immunology pipeline and partnerships across a broad range of therapeutic areas. The work here is highly collaborative, fast-moving, and grounded in the belief that breakthroughs happen when strong science, thoughtful technology, and great people work closely together.

Position Summary:

Terray Therapeutics is seeking a motivated, creative, and experienced immunologist to join our cell assay team. This role will be full-time onsite. The candidate will work with other scientists in the team to design experiments to evaluate the mechanism of action of hits from Terray’s proprietary EMMI platform and optimize assays to support program progression through hit-to-lead and lead optimization. The successful candidate will have a strong immunology background and understanding of immune signaling pathways along with demonstrated experience applying a broad range of cellular techniques to probe small molecule mechanism of action.

The Core Responsibilities Of This Position Are

• Review the literature to gain a comprehensive understanding of internal therapeutic targets of interest
• Design experiments to confirm the mechanism of action of small molecule hits from our binding and virtual screens in cells
• Independently develop, optimize, and run cell-based assays to profile on- and off-target activity of hits and hit series
• Adapt assays for medium to high-throughput screening and IC50 generation to support structure-activity-relationship understanding
• Manage CROs for reagent development and/or in vitro testing as needed
• Analyze and interpret experimental data and communicate results in project team meetings
• Interface with a multidisciplinary team (including chemists and computational scientists) as the immunology representative to drive decision-making
• Support organization of lab and equipment as needed

Experience and Qualifications:

Given the company’s size, anticipated growth and fast-paced environment, the organization requires a scientist who is thoughtful, high energy, attentive to detail, and can work effectively with the biology team to further enhance our next-generation drug discovery capabilities.

Part of Terray’s success is nurtured by a hands-on work environment where everyone is accountable, vested in a vision of excellence, and actively taking part in the success of the business. Terray supports a positive work environment where employees can feel engaged,recognizedand empowered to be creative.

Required Qualifications

• PhD in the field of immunology, molecular or cell biology, or related field with 3+ years of small molecule drug discovery experience
• Or MSc with 10+ years of small molecule drug discovery industry experience
• Strong background in immunology and immune signaling pathways
• Extensive hands‑on experience with cell culture and cell‑based assays, including reporter assays, gene and protein expression (eg: Flow cytometry, qPCR, RNAseq, Luminex, MSD, ELISA, Western) and intracellular techniques
• Proficiency in primary cell isolation, differentiation, culture and flow cytometry
• Experience establishing robust assays for small molecule dose responses and IC50 generation
• Excellent organizational, interpersonal and communication skills, and can thrive in a highly collaborative research environment
• Demonstrated technical proficiency, ability to troubleshoot to solve problems and to deliver high quality data

Candidates will exhibit the ability to work well under pressure to provide results in a short timeframe. The company is looking for a highly responsive, goal‑oriented individual who will bring significant energy and drive to solve complex technical problems and help us achieve our mission to advance human health.

Compensation Details:

$120,000 – $175,000 annually, depending on experience. Terray’s salary ranges are designed to be competitive and are benchmarked against market base salary plus bonus within our industry and market. We align pay to role scope, skill level, and impact.

We invest heavily in benefits because taking care of our people matters. Our programs are benchmarked at the top of the Southern California market and designed to provide meaningful support across every stage of life.

• participation in the Company’s stock option plan
• a 3% retirement safe harbor contribution
• fully paid health, dental, and vision insurance for our employees, spouse, partner, and families
• above‑market life insurance
• disability coverage
• and much more to explore during the offer process